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Binglong Zhang at work in the lab
MSK researchers continued to make strides against cancer in 2025. Learn about some of their top discoveries.
Dr. Omar Abdel-Wahab in his lab
Q&A
A leader in developing better treatments for a range of blood cancers, Dr. Omar Abdel-Wahab is only the second person from MSK to receive the Paul Marks Prize for Cancer Research. 
Lab coat with the MSK logo hangs in a lab
MSK Research Highlights, November 20, 2025
New MSK research finds a potential therapeutic opportunity in regulatory T cells’ resilience to the loss of Foxp3; shows how cancer develops resistance to antibody-drug conjugates; develops a new system to help make gene editing safer and more reliable; and shows provider billing margin doesn’t drive cancer treatment selection.
A researcher points to cells on a screen
In 2025, MSK was again ranked among the top organizations with the greatest number of highly cited scientific researchers worldwide, according to the annual list of Highly Cited Researchers, published by the Institute for Scientific Information at Clarivate.
Microscope in foreground. GSK Graduate Students in the background.
Since its founding 19 years ago, the Gerstner Sloan Kettering Graduate School of Biomedical Sciences has attracted bright minds drawn to its connection to MSK. Learn more about how we're training tomorrow's leaders.
hematopoietic stem and progenitor cells
VEXAS syndrome is a confounding adult-onset inflammatory disease first described in 2020, which affects 1 in 4,000 men over 50. Now, MSK researchers are shedding new light on its mechanisms and laying the groundwork for potential targeted treatments.
A researcher working in an MSK lab
MSK Research Highlights, September 25, 2025
New MSK research highlights the importance of tumor location in metastasis; shows how regulatory T cells work with sensory nerves in the skin to restrain pain and inflammation; explores whether a large language model can adequately summarize cancer patients’ experiences with pain; and finds proton therapy is effective at treating leptomeningeal metastasis.
Zhi “Zack” Zheng
This year's GSK Chairman’s Prize was awarded to Zhi “Zack” Zheng for his research on the SPO11 protein, which creates double-strand breaks in DNA.
An MSK researcher points to a scientific image on a screen
New MSK research develops a powerful new resource for studying gene regulation across eukaryotes; uncovers how “jumping genes” can drive cancer growth; describes how an unexpected oxygen sensor regulates ferroptosis; establishes a technique to map chromatin architecture in 3D; creates new models for studying schizophrenia-associated defects; and finds transcription factor 19 is critical for the responses of natural killer cells to viral infection.
Joan Massagué
Sloan Kettering Institute Director Dr. Joan Massagué talks about our updated understanding of cancer metastasis.