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MSK Research Highlights, April 23, 2025

New MSK research identifies a rare cell population responsible for AML persistence and resistance to therapy; sheds new light on early brain development; and investigates how other health conditions can increase cancer risk in midlife. MSK clinical trials also supported the recent approval of the targeted drug larotrectinib by the FDA.

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Circulating Tumor Cells May Spur Cancer by a Previously Unknown Mechanism

A recent Memorial Sloan Kettering study shows that some circulating tumor cells can circle back and infiltrate their tumor of origin, enhancing its growth and aggressiveness.

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5 Reasons Boys and Young Men Need the HPV Vaccine, Too

If you think women are the only people who get cancers caused by the human papillomavirus (HPV), think again. These cancers are on the rise in men.

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Meet Jun Mao, MSK’s Chief of Integrative Medicine

Dr. Mao leads a team of integrative medicine specialists who offer complementary therapies such as massage and acupuncture to patients and caregivers.

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Quadruplet Therapy Significantly Improved Outcomes in Transplant-Ineligible Myeloma

A five-year study has found that adding daratumumab (D) to the current standard-of-care triplet therapy bortezomib, lenalidomide, and dexamethasone (VRd) produced deeper and more durable minimal residual disease (MRD) responses compared to VRd alone in patients with newly diagnosed, transplant-ineligible multiple myeloma.

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Researchers Discover Why New Melanoma Drug Stops Working

Research led by investigators at Memorial Sloan Kettering has identified a previously unknown mechanism of resistance to the newly approved melanoma drug, vemurafenib.

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Memorial Sloan Kettering Shares Historic Gift to Fund Immunotherapy Research

Immunologist Alexander Rudensky and medical oncologist and immunologist Jedd Wolchok are investigating innovative ways to use the immune system to fight cancer.

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MSK Innovation: New Ventilator Designed to Provide Respiratory Support in Emergencies

A multidisciplinary team at Memorial Sloan Kettering Cancer Center (MSK) has developed a proof-of-concept crisis ventilator intended to provide lifesaving breathing assistance to patients requiring it when more-sophisticated respiratory support equipment is unavailable.

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GSK Fourth Biennial Retreat

GSK students, alumni, faculty, and guest speakers enjoyed two days of presentations, panel discussions, a poster session, recreation and socializing at the school’s fourth biennial retreat.

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What You Should Know about Metastatic Breast Cancer

Medical oncologist Chau Dang explains that patients living with metastatic breast cancer have more treatment options than ever before.

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