Associate Professor (with tenure), 2020–present
Assistant Professor, 2014–2020
Department of Chemistry & Biochemistry,
University of Oklahoma
Lucille Castori Postdoctoral Fellow, 2012–2014
PhD, Wayne State University, 2011
MSc, IIT–Kharagpur, 2006
BSc, University of Delhi, 2004
Publications
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Mechanism of MenE inhibition by acyl-adenylate analogues and discovery of novel antibacterial agents.
Matarlo, J. S.; Evans, C. E.; Sharma, I.; Lavaud, L. J.; Ngo, S. C.; Shek, R.; Rajashankar, K. R.; French, J. B.; Tan, D. S.*; Tonge, P. J.* Biochemistry 2015, 54, 6514–6524.
[ Abstract | PubMed | PMC ] -
Solvent-dependent divergent functions of Sc(OTf)3 in stereoselective epoxide-opening spiroketalizations.
Sharma, I.; Wurst, J. M.; Tan, D. S.* Org. Lett. 2014, 16, 2474–2477.
[ Abstract | PubMed | PMC ] -
Diversifying complexity.
Sharma, I.; Tan, D. S.* Nat. Chem. 2013, 5, 157–158.
[ Abstract | PubMed ] -
Stable analogues of OSB-AMP: Potent inhibitors of MenE, the o-succinylbenzoate-CoA synthetase from bacterial menaquninone biosynthesis.
Lu, X.; Zhou, R.; Sharma, I.; Li, X.; Kumar, G.; Swaminathan, S.; Tonge, P. J.*; Tan, D. S.* ChemBioChem 2012, 13, 129–136.
[ Abstract | PubMed | PMC ] -
Influence of protecting groups on the anomeric equilibrium; case of the 4,6-O-benzylidene acetal in the mannopyranose series.
Sharma, I.; Bohé, L.; Crich, D.* Carbohyd. Res. 2012, 357, 126–131.
[ Abstract | PubMed | PMC ] -
Direct Fmoc-chemistry-based solid-phase synthesis of peptidyl thioesters.
Sharma, I.; Crich, D.* J. Org. Chem. 2011, 76, 6518–6524.
[ Abstract | PubMed | PMC ] -
Influence of protecting groups on the reactivity and selectivity of glycosylation: chemistry of the 4,6-O-benzylidene protected mannopyranosyl donors and related species.
Aubry, S.; Sasaki, K.; Sharma, I.; Crich, D.* Topics Curr. Chem. 2011, 301, 141–188.
[ Abstract | PubMed ] -
Influence of the O3 protecting group on stereoselectivity in the preparation of C-mannopyranosides with 4,6-O-benzylidene protected donors.
Crich, D.*; Sharma, I. J. Org. Chem. 2010, 75, 8383–8391.
[ Abstract | PubMed | PMC ] -
Triblock peptide and peptide thioester synthesis with reactivity-differentiated sulfonamides and peptidyl thioacids.
Crich, D.*; Sharma, I. Angew. Chem. Intl. Ed. 2009, 48, 7591–7594.
[ Abstract | PubMed | PMC ] -
Epimerization-free block synthesis of peptides from thioacids and amines with the Sanger and Mukaiyama reagents.
Crich, D.*; Sharma, I. Angew. Chem. Intl. Ed. 2009, 48, 2355–2358.
[ Abstract | PubMed ] -
Is donor-acceptor hydrogen bonding necessary for 4,6-O-benzylidene-directed β-mannopyranosylation? Stereoselective synthesis of β-C-mannopyranosides and α-C-glucopyranosides.
Crich, D.*; Sharma, I. Org. Lett. 2008, 10, 4731–4734.
[ Abstract | PubMed | PMC ] -
Direct access to 1,4-dihydroxyanthraquinones: The Hauser annulation reexamined with p-quinones.
Mal, D.*; Ray, S.; Sharma, I. J. Org. Chem. 2007, 72, 4981–4984.
[ Abstract | PubMed ]
