The John Petrini Lab: Publications

Visit PubMed for a full listing of John Petrini’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Balestrini, A., Ristic, D., Dionne, I., Liu, X., Wyman, C., Wellinger, R.C., Petrini, J.H. (2013) The Ku heterodimer and the metabolism of single-ended DNA double strand breaks. Cell Reports, 3. 2033-45. PMCID: PMC3815622

Ballew, B., Joseph, V., De, S., Sarek, G., Vannier, J-B., Stracker, T., Schrader, K.A., Small, T.N., O’Reilly, R., Manschreck, C., Harlan Fleischut, M.M., Sullivan, J., Stratton, K., Yeager, M., Jacobs, K., Giri, N., Alter, B.P., Boland, J., Burdett, L., Offit, K., Boulton, S., Savage, S.A., Petrini, J.H.J.  (2013) A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1, RTEL1, Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome.  PLoS Genetics, 8.: e1003695 PMCID: PMC3757051

Gupta, G., Vanness, K., Barlas, A., Manova-Todorova, K., Wen, Y.H., Petrini, J.H. (2013) The Mre11 Complex Suppresses Oncogene-driven Breast Tumorigenisis and Metastasis. Mol Cell 52. 353-365 PMCID: PMC3902959

Roset, R., Inagaki, A., Hohl, M., Brenet, F., Lafrance-Vanasse, J., Lange, J., Scandura, J., Tainer, J., Keeney, S., Petrini, J.H. (2014) The Rad50 hook domain regulates DNA damage signaling and tumorigenesis. Genes Dev, 28. 451-462 PMCID: PMC3950343

Al-Ahmadie, H., Iyer, G., Hohl, M., Inagaki, A., Shultz N., Hanrahan, AJ., Scott, S.N., Brannon, A.R., McDermott, G.C., Pirun, M., Ostrovnaya, I., Kim, P., Socci, N.D., Viale, A., Schwartz, G.K., Reuter, V., Bochner, B.H., Rosenberg, JE., Bajorin, DF., Berger, M.F., Petrini, J.H.J., Solit, D.B., Taylor, B.S. (2014) Synthetic lethality in ATM-deficient RAD50-mutant tumors underlie outlier response to cancer therapy.  Cancer Discov. 9. 1014-1021 PMCID: PMC4155059

Hohl, M., Kochanczyk, T., Tous, C., Aguilera, A., Krezel, A. Petrini, J.H. (2015) Interdependence of the Rad50 hook and globular domain functions. Mol. Cell. 57: 479-491. PMCID: PMC4527088

Inagaki, A., Roset, R., Petrini, J.H. (2015) Functions of the MRE11 complex in the development and maintenance of oocytes. Chromosoma. 125. 151-162. PMCID: PMC4734907

Balestrini, A., Nicolas, L., Yang-Lott, K., Guryanova, O., Levine, R., Bassing, C., Chaudhuri, J., Petrini, J.H. (2015) Defining ATM-independent Functions of the Mre11 Complex with Novel Mouse Model. Mol Cancer Res. 14. 185-95. PMCID: PMC4755792

Asai, T., Hatlen M. A., Lossos, C., Ndiaye-Lobry, D., Deblasio, A., Murata, K., Fleisher, M., Cortizas, E. M., Verdun, R. E., Petrini, J.H., Nimer, S. (2016) Generation of novel, multi-stage progressive, and transplantable model of plasma cells neoplasms. Sci. Rep. 6, 22760; doi: 10.1038/srep22760. PMCID: PMC4785351

Park YB, Hohl, M., Padjasek, M., Jeong, E., Kyeong J.S., Kretzel, A., Petrini, J.H., Cho, Y., (2016) Eukaryotic Rad50 Functions as a Rod-shaped Dimer. Nat Struct Mol Biol (3) 248-257 PMCID: PMC5625350

Kim, JH., Grosbart, M., Anand, R., Wyman C., Cejka, P., Petrini, J.H., (2017) The Mre11-Nbs1 interface is essential for viability and tumor suppression. Cell Rep. 18. (2) 496-507 PMCID: PMC5234850

Henssen, A. G., Reed, C., Jiang, E., Garcia, H.D., von Stebut, J., MacArthur, I.C., Hundsdoerfer, P., Kim, J.H., de Stanchina, E., Kuwahara, Y., Hosoi, H., Ganem, N., Dela Cruz, F., Kung, A. L., Schulte, J.H.,  Petrini J.H., Kentsis, A. (2017) Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid Tumors. Science Transl Med. 9 (414) DOI: 10.1126/scitranslmed.aam9078 PMCID: PMC5683417