Wang YT, Trzeciak AJ, Rojas WS, Saavedra P, Chen YT, Chirayil R, Etchegaray JI, Lucas CD, Puleston DJ, Keshari KR, Perry JSA. Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments. Cell Metab. 2023 Feb 7;35(2):316-331.e6. doi: 10.1016/j.cmet.2022.12.005. Epub 2022 Dec 29.
Raymond MH, Davidson AJ, Shen Y, Tudor DR, Lucas CD, Morioka S, Perry JSA*, Krapivkina J, Perrais D, Schumacher LJ, Campbell RE, Wood W, Ravichandran KS. Live cell tracking of macrophage efferocytosis during Drosophila embryo development in vivo. Science. 2022 Mar 11 ;375(6585):1182-1187.
Trzeciak A, Wang YT, Perry JSA*. First we eat, then we do everything else: The dynamic metabolic regulation of efferocytosis. Cell Metab. 2021 Nov 2 ;33(11):2126-2141.
Arandjelovic S, Perry JSA*, Zhou M, Ceroi A, Smirnov I, Walk SF, Shankman LS, Cambré I, Onengut-Gumuscu S, Elewaut D, Conrads TP, Ravichandran KS. ELMO1 signaling is a promoter of osteoclast function and bone loss. Nat Commun. 2021 Aug 17 ;12(1):4974.
Medina CB, Malhotra P, Arandjelovic S, Perry JSA*, Guo Y, Morioka S, Barron B, Walk SF, Ghesquiere B, Krupnick AS, Lorenz U, Ravichandran KS. Metabolites released from apoptotic cells act as tissue messengers. Nature. 2020, 580:130-135. *equal contribution.
Yao, M, Ventura, PB, Jiang, Y, Rodriguez, FJ, Wang, L., Perry, JSA, Yang, Y, Wahl, K, Crittenden, RW, Bennett, ML, Qi, L, Gong, C-C, Li, X-N, Barres, BA, Bender, TP, Ravichandran, KS, Janes, KA, Eberhart, CG, Zong, H. Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth. Cell. 2020, 180:502-520.
Perry, JSA*, Morioka, S*, Medina, C, Etchegaray, JI, Barron, B, Raymond, MH, Lucas, CD, Onengut-Gumuscu, S, Delpire, E, Ravichandran, KS. Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway. Nature Cell Biology. 2019, 21:1532-1543. *equal contribution.
Morioka, S*, Perry, JSA*, Raymond, MH, Medina, C, Onengut-Gumuscu, S, Ravichandran, KS. Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release. Nature. 2018, 563:714-718. *equal contribution.
Arandjelovic, S, Perry, JSA, Penberthy, KK, Walk, SF, Kim, T-H, Chuang, T-Y, Cambré, I, Onengut-Gumuscu, S, Gaultier, A, Elewaut, D, Kim, M, Elliott, MR, Ravichandran, KS. Unexpected linkage of a cell clearance module to promoting inflammatory arthritis. Nature Immunology. 2018, 20:141-151.
Gururaj, S, Urbanek, K, Przanowski, P, Perry, JSA, Jones, J, Haggert, R, Kostka, C, Patki, T, Stelow, EB, Petrova, Y, Llaneza, D, Mayo, M, Ravichandran, KS, Landen, CN, Bhatnagar, S, Tushir-Singh, J. A single-agent dual-specificity targeting of FOLR1 and DR5 as an effective strategy for ovarian cancer. Cancer Cell. 2018, 34:331-345.
Perry, JSA, Russler-Germain, EV, Zhou, YW, Purtha, W, Cooper, ML, Choi, J, Salazar, V, Egawa, T, Lee, B-C, Abumrad, NA, Kim, B, Anderson, M, DiPersio, JF, Hsieh. C-S. Transfer of cell-surface antigens by scavenger receptor CD36 promotes thymic tegulatory T cell receptor repertoire development and allo-tolerance. Immunity. 2018, 48:923-936.
Oh, J, Perry, JSA, Pua, H, Irgens-Moller, N, Ishido, S, Hsieh, C-S, Shin, J-S. Role of MHCII ubiquitination in maintaining lipid raft homeostasis in dendritic cells. Journal of Cell Biology. 2018, 217:1395-1410.
Penberthy, KK, Rival, C, Shankman, LS, Raymond, MH, Zhang, J, Perry, JSA, Han, CZ, Lysiak, JJ, Onengut-Gumusco, S, Palczewski, K, Ravichandran, KS. Context-dependent compensation among phosphatidylserine-recognition receptors. Scientific Reports. 2017, 7:14623.
Chai, JN, Peng, Y, Rengarajan, S, Solomon. BD, Ai, TL, Shen, Z, Perry, JSA, Knoop, KA, Tanoue, T, Narushima, S, Honda, K, Elson, CO, Newberry, RD, Stappenbeck, TS, Kau, AL, Peterson, DA, Fox, JG, Hsieh, C-S. Helicobacter species are potent drivers of colonic T cell responses in homeostasis and inflammation. Science Immunology. 2017, 2:eaal5068.
Waters, R, Perry, JSA, Han, S, Bielekova, B, Gedeon, T. The effects of interleukin-2 on immune response regulation. Math Med Biol. 2017, 35:79-119.
Perry, JSA, Ravichandran, KS. Embryonic trogocytosis: Neighborly nibbling during development. Current Biology. 2017, 27:R68-R70.
Perry, JSA, Hsieh, C-S. Development of T cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen. Immunological Reviews, Special Issue: The Thymus, Lymph nodes, and Lymphatics. 2016, 271:141-155.
Perry, JSA, Lio, C-WJ, Kau, AL, Nutsch, K, Yang, Z, Gordon, JL, Murphy, KM, Hsieh, C-S. Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus. Immunity, 2014, 41:414-426.
Perry, JSA, Han, S, Xu, Q, Herman, M, Kennedy, L-B, Csako, G, Bielekova, B. Inhibition of LTi Cell Development by CD25 Blockade Is Associated with Decreased Intrathecal Inflammation in Multiple Sclerosis Science Translational Medicine. 2012, 4:145ra106.
Wuest, SC, Edwan, JH, Martin, JF, Han, S, Perry, JSA, Cartagene CM, Matsuura, E, Maric D, Waldmann, TA, Bielekova, B. A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy. Nature Medicine, 2011, 17:604-609.
Martin, J, Perry, JSA, Jakhete, N, Wang, X, Bielekova, B. An IL-2 paradox: Blocking CD25 induces IL-2-driven activation of CD56bright NK cells. Journal of Immunology, 2010, 185:1311-1320.