The Mary Baylies Lab

Mary Baylies Lab

Developmental biologist Mary Baylies studies the mechanisms that form and maintain muscle both during normal development and in disease.

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Selected Achievements

  • Developed a Drosophila model for metastasis in alveolar rhabdomyosarcoma, a type of soft tissue cancer most often seen in children
  • Demonstrated that properly placed nuclei are critical for healthy muscle function
  • Described how nuclear polarization occurs during myonuclear movement in vivo
  • Completed the first spatial and temporal characterization of an F-actin structure that forms at the myoblast fusion site
  • Identified transcription factors and chromatin regulators that are critical for muscle identity

  • Identified 3-D arrangement of myoblasts that occur during muscle specification and morphogenesis
  • Discovered signal transduction pathways (Notch, Wnt, BMP, and RTK) and transcription factors that are critical for muscle identity
  • President of the Society for Muscle Development (2009-2013)
  • Frederick Adler Chair for Junior Faculty (1997-2003)