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Anton Dobrin, PhD

Postdoctoral Fellow, Memorial Sloan Kettering Cancer Center, New York, NY

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Anton Dobrin

Email

[email protected]

URL

Dissertation

Antigen Agnostic Co-Stimulation for Engineered TCR T-Cells

Mentor

Michel Sadelain, MD, PhD

Start Year

2015

End Year

2023

Education

BS, University of Toronto; MS, Swiss Federal Institute of Technology Zurich

Fellowships

Geoffrey Beene Graduate Student Fellowship (2016-2017)
Canadian Institutes of Health Research Doctoral Research Award 2017-2020

Publications

Mansilla-Soto J, Eyquem J, Haubner S, Hamieh M, Feucht J, Paillon N, Zucchetti AE, Li Z, Sjöstrand M, Lindenbergh PL, Saetersmoen M, Dobrin A, Maurin M, Iyer A, Garcia Angus A, Miele MM, Zhao Z, Giavridis T, van der Stegen SJC, Tamzalit F, Rivière I, Huse M, Hendrickson RC, Hivroz C, Sadelain M; HLA-independent T cell receptors for targeting tumors with low antigen density.; Nature medicine; 2022; 28(2):345-352; PubMed ID: 35027758

Łuksza M, Sethna ZM, Rojas LA, Lihm J, Bravi B, Elhanati Y, Soares K, Amisaki M, Dobrin A, Hoyos D, Guasp P, Zebboudj A, Yu R, Chandra AK, Waters T, Odgerel Z, Leung J, Kappagantula R, Makohon-Moore A, Johns A, Gill A, Gigoux M, Wolchok J, Merghoub T, Sadelain M, Patterson E, Monasson R, Mora T, Walczak AM, Cocco S, Iacobuzio-Donahue C, Greenbaum BD, Balachandran VP. (2022) Neoantigen quality predicts immunoediting in survivors of pancreatic cancer. Nature.

Hamieh M, Dobrin A, Cabriolu A, van der Stegen SJC, Giavridis T, Mansilla-Soto J, Eyquem J, Zhao Z, Whitlock BM, Miele MM, Li Z, Cunanan KM, Huse M, Hendrickson RC, Wang X, Rivière I, Sadelain M. (2019) CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape. Nature. 568, 112-116.

Green JA, Arpaia N, Schizas M, Dobrin A, Rudensky AY; A nonimmune function of T cells in promoting lung tumor progression.; The Journal of experimental medicine; 2017

Feucht J, Sun J, Eyquem J, Ho YJ, Zhao Z, Leibold J, Dobrin A, Cabriolu A, Hamieh M, Sadelain M. (2018) Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency. Nat Med.

View a full listing of Anton Dobrin’s journal articles.