Georgina Berrozpe, MD, PhD

Senior Research Scientist

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2022

Publications

Direct engagement of the PI3K pathway by mutant KIT dominates oncogenic signaling in gastrointestinal stromal tumor. Bosbach B, Rossi F, Yozgat Y, Loo J, Zhang JQ, Berrozpe G, Warpinski K, Ehlers I, Veach D, Kwok A, Manova K, Antonescu CR, DeMatteo RP, Besmer P. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8448-E8457. doi: 10.1073/pnas.1711449114. [PMID: 28923937] 

OCT4 and SOX2 Work as Transcriptional Activators in Reprogramming Human Fibroblasts. Narayan S, Bryant G, Shah S, Berrozpe G, Ptashne M. Cell Rep. 2017 Aug 15;20(7):1585-1596. doi: 10.1016/j.celrep.2017.07.071. [PMID: 28813671] 

Polycomb Responds to Low Levels of Transcription. Berrozpe G, Bryant GO, Warpinski K, Spagna D, Narayan S, Shah S, Ptashne M. Cell Rep. 2017 Jul 25;20(4):785-793. doi: 10.1016/j.celrep.2017.06.076. [PMID: 28746865] 

Regulation of a mammalian gene bearing a CpG island promoter and a distal enhancer. Berrozpe G, Bryant GO, Warpinski K, Ptashne M. Cell Rep. 2013 Aug 15;4(3):445-53. doi: 10.1016/j.celrep.2013.07.001. [PMID: 23911283] 

A RSC/nucleosome complex determines chromatin architecture and facilitates activator binding. Floer M, Wang X, Prabhu V, Berrozpe G, Narayan S, Spagna D, Alvarez D, Kendall J, Krasnitz A, Stepansky A, Hicks J, Bryant GO, Ptashne M. Cell. 2010 Apr 30;141(3):407-18. doi: 10.1016/j.cell.2010.03.048. [PMID: 20434983] 

A distant upstream locus control region is critical for expression of the Kit receptor gene in mast cells. Berrozpe G, Agosti V, Tucker C, Blanpain C, Manova K, Besmer P. Mol Cell Biol. 2006 Aug;26(15):5850-60. doi: 10.1128/MCB.01854-05. [PMID: 16847336]