Email boyerj@sloankettering.edu Mentor Neal Rosen, MD, PhD Start Year 2014 Education BS, Pennsylvania State University Research Focus Adaptation of cells to mTOR inhibition and development of mTORC1 selective inhibitors. Fellowships Grayer Fellowship (2016-2017) Geoffrey Beene Graduate Student Fellowship (2015-2016) Publications Mukherjee R, Vanaja KG, Boyer JA, Gadal S, Solomon H, Chandarlapaty S, Levchenko A, Rosen N. (2021) Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis. Mol Cell 84, 708-723. Amor C, Feucht J, Leibold J, Ho YJ, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, Peerschke E, Friedman SL, Ponomarev V, Piersigilli A, Sadelain M, Lowe SW; (2020) Senolytic CAR T Cells Reverse Senescence-Associated Pathologies Nature 583. 127-132. Smith KJ, Murray IA, Boyer JA, Perdew GH. (2017) Allelic variants of the aryl hydrocarbon receptor differentially influence UVB-mediated skin inflammatory responses in SKH1 mice. Toxicology, 394, 27-34. PMCID: PMC5756104 Smith KJ, Boyer JA, Muku GE, Murray IA, Gowda K, Desai D, Amin SG, Glick AB, Perdew GH. (2017) Ah receptor activation potentiates neutrophil chemoattractant (C-X-C motif) ligand 5 expression in keratinocytes and skin. Toxicol Sci., 160, 83-94. PMCID: PMC5837612 Lahoti TS, Boyer JA, Kusnadi A, Muku GE, Murray IA, Perdew GH. (2015) Aryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c-c motif) Ligand 20. Toxicol Sci., 148, 229-40. PMCID: PMC4731409.
