Chemical Biology Program
The Minkui Luo Lab
Research
The Luo Lab is interested in developing and leveraging novel approaches at the interface of chemistry and biology to annotate functional roles of epigenetic modulators. Epigenetic regulation is essential for maintaining cellular fates and its dysregulation has been associated with various diseases including cancer. Among key epigenetic modulators are diverse protein methyltransferases/demethylases and methyl-arginine/lysine (Rme/Kme) effector proteins. With novel chemical tools developed in-house, we aim to systematically interrogate Rme/Kme-involved epigenetics with emphasis on novel molecular mechanisms and biological outcomes. The Luo laboratory is also interested in designing and synthesizing epigenetic inhibitors with the emphasis of the distinct modes of action in disease-relevant contexts. Researchers in the Luo Lab with expertise in chemistry, biochemistry and biology work in a highly collaborative manner to develop unprecedent chemical reagents for biological discovery, elucidate disease-causing mechanisms with molecular details, and explore novel treatments against cancer.
Featured News
People
Minkui Luo, PhD
- Chemical Biologist Minkui Luo develops cutting-edge tools, technologies and concepts to annotate functions of protein-posttranslational modifications and designs inhibitors for cancer therapies.
- BS, Fudan University
- PhD, Princeton University
- luom@mskcc.org
- Email Address
- 646-888-3066
- Office Phone
- Download CV
- PDF File
Members
Lab Head
Research Technician
Former Research Fellow
Research Fellow
Senior Research Assistant
Administrative Assistant
Senior Research Scientist
Graduate Student
Research Fellow
Lab Alumni
Administration Assistant
Graduate Student
Graduate Student
Graduate Student
Senior Research Scientist
Postdoctoral Fellow
Postdoctoral Fellow
Postdoctoral Fellow
Postdoctoral Fellow
Visiting Professor
Visiting Investigator
Graduate Student
Joint Graduate Student with the Gudas Lab
Joint Postdoctoral Fellow with the Zhao Lab
Research Fellow
Research Fellow
Senior Laboratory Technician
Graduate Student
Research Fellow
Graduate Student
Research Fellow
Research Fellow
Research Fellow
Graduate Student
Research Fellow
Visiting Investigator
Research Fellow
Research Fellow
Research Fellow
Graduate Research Student
Lab Affiliations
Achievements
- Maximizing Investigators’ Research Award (R35), NIGMS/NIH (2019)
- Eli Lilly Award in Biological Chemistry, American Chemical Society (2015)
- Clinical & Translational Science Center Novel Award, Weill Cornell Medical College (2014)
- Basil O'Connor Starter Scholar, March of Dimes Birth Defects Foundation (2011)
- Director’s New Innovator Award, National Institutes of Health (2010)
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- Alfred W. Bressler Scholar, Alfred W. Bressler Scholars Endowment Fund (2010)
- The V Scholar Award, V Foundation for Cancer Research (2009)
- Outstanding Postdoctoral Research Prize, Albert Einstein College of Medicine (2007)
- Best Presentation Award, 3rd ACS Annual Metropolitan New York Area Poster Program for Graduate Students in the Chemical Sciences (2003)
- Rohm & Haas Fellowship, Fudan University (1998)
- Du Pont Fellowship, Fudan University (1998)
