Structural Biology Program
The Richard Hite Lab
Our research group is focused upon determining the mechanisms of intracellular ion transport with a particular focus upon the lysosome. We use a variety of structural and biophysical tools including cryo-electron microscopy, X-ray crystallography and electrophysiology to characterize these channels.
Paknejad N and Hite RK. “Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3.” Nat Struct Mol Biol. 2018. 25:660-668.
Oh S, Paknejad N and Hite RK. “Gating and Selectivity Mechanisms for the Lysosomal K + Channel TMEM175.” eLife. 2020. 9:e53430.
Richard Hite, PhD
- The Hite laboratory studies the mechanisms of intracellular ion transport.
- BS - Emory University
- PhD – Harvard University
- Josie Robertson Investigator
- Searle Scholar
- Tri-Institutional Breakout Award for Junior Investigators
Graduate Students & Postdoctoral Fellows
Positions are available for graduate students and postdoctoral fellows to study in the research group of Richard Hite at Memorial Sloan Kettering Cancer Center to study ion channel structure, function and physiology.
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Richard Hite discloses the following relationships and financial interests:
No disclosures meeting criteria for time period
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.