Bodo S, Campagne C, Thin TH, Higginson DS, Vargas HA, Hua G, Fuller JD, Ackerstaff E, Russell J, Zhang Z, Klingler S, Cho H, Kaag MG, Mazaheri Y, Rimner A, Manova-Todorova K, Epel B, Zatcky J, Cleary CR, Rao SS, Yamada Y, Zelefsky MJ, Halpern HJ, Koutcher JA, Cordon-Cardo C, Greco C, Haimovitz-Friedman A, Sala E, Powell SN, Kolesnick R, Fuks Z. Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury. J Clin Invest. 2018; pii: 97631. Martin ML, Zeng Z, Adileh M, Jacobo A, Li C, Vakiani E, Hua G, Zhang L, Haimovitz-Friedman A, Fuks Z, Kolesnick R*, Paty PB*. Logarithmic expansion of LGR5+ cells in human colorectal cancer. Cell Signal. 2018; 42:97-105. doi: 10.1016/j.cellsig.2017.09.018. * Equal co-author. Van Hell AJ, Haimovitz-Friedman A, Fuks Z, Tap WD, Kolesnick R. Gemcitabine kills proliferating endothelial cells exclusively via acid sphingomyelinase activation. Cell Signal. 2017; 34:86-91. doi: 10.1016/j.cellsig.2017.02.021. Zhang L, Adileh M, Martin ML, Klingler S, White J, Ma X, Howe LR, Brown AM, Kolesnick R. Establishing estrogen-responsive mouse mammary organoids from single Lgr5+ cells. Cell Signal. 2017; 29:41-51. doi: 10.1016/j.cellsig.2016.08.001. Hua G, Yan Pan CW, Zeng Z, Lee SG, Martin ML, Haimovitz-Friedman A, Fuks Z, Paty PB, Kolesnick R. Distinct levels of radioresistance in Lgr5+ colonic epithelial stem cells versus Lgr5+ small intestinal stem cells. Cancer Res 2017; 77:2124-2133. doi: 10.1158/0008-5472.CAN-15-2870. Mertelsmann AM, Lindemans CA, O’Connor MH,Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G, Ivanov J, Luo N, Hua G, Martin ML, Farin H, Liu C, Clevers H, Kolesnick R, van den Brink MRM, Hanash AM. Interleukin-22 Is an Intestinal Stem Cell Growth Factor Linking Immunity to Epithelial Regeneration. Nature. 2015; 528:560-4. doi: 10.1038/nature16460. Deng X, Michaelson D, Tchieu J, Cheng J, Rothenstein D, Feldman R, Lee SG, Fuller J, Haimovitz-Friedman A, Studer L, Powell S, Fuks Z, Hubbard EJ, Kolesnick R.; Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors. PLoS One. 2015; 10:e0127862. doi: 10.1371/journal.pone.0127862. eCollection 2015. Hla, T and Kolesnick, R.; C16:0-Ceramide Signals Insulin Resistance. Cell Metabolism. 2014; 20:703-705. Gulbins E, Kolesnick R.; It takes a CAD to kill a tumor cell with a LMP.; Cancer Cell. 2013;24:279-281. Hua G, Thin TH, Feldman R, Haimovitz–Friedman A, Clevers H, Fuks Z, Kolesnick R. Crypt base columnar stem cells in small intestines of mice are radioresistant. Gastroenterology. 2012;143:1266-76. PMCID: PMC3480544. Rotolo J, Stancevic B, Zhang J, Hua G, Fuller J, Yin X, Haimovitz-Friedman A, Kim K, Qian M, Cardó-Vila M, Fuks Z, Pasqualini R*, Arap W*, Kolesnick R*. Anti-ceramide Antibody Prevents The Radiation GI Syndrome in Mice. J Clin Invest. 2012; 122:1786-90. *Equal co-authors. Book traversal links for The Richard Kolesnick Lab Previous Featured News