The Richard Kolesnick Lab: Publications

Martin ML, Zeng Z, Adileh M, Jacobo A, Li C, Vakiani E, Hua G, Zhang L, Haimovitz-Friedman A, Fuks Z, Kolesnick R*, Paty PB*. Logarithmic expansion of LGR5+ cells in human colorectal cancer. Cell Signal. 2018; 42:97-105. doi: 10.1016/j.cellsig.2017.09.018. * Equal co-author

Van Hell AJ, Haimovitz-Friedman A, Fuks Z, Tap WD, Kolesnick R. Gemcitabine kills proliferating endothelial cells exclusively via acid sphingomyelinase activation. Cell Signal. 2017; 34:86-91. doi: 10.1016/j.cellsig.2017.02.021.

Zhang L, Adileh M, Martin ML, Klingler S, White J, Ma X, Howe LR, Brown AM, Kolesnick R. Establishing estrogen-responsive mouse mammary organoids from single Lgr5+ cells. Cell Signal. 2017; 29:41-51. doi: 10.1016/j.cellsig.2016.08.001.

Hua G, Yan Pan CW, Zeng Z, Lee SG, Martin ML, Haimovitz-Friedman A, Fuks Z, Paty PB, Kolesnick R. Distinct levels of radioresistance in Lgr5+ colonic epithelial stem cells versus Lgr5+ small intestinal stem cells. Cancer Res 2017; 77:2124-2133. doi: 10.1158/0008-5472.CAN-15-2870.

Mertelsmann AM, Lindemans CA, O’Connor MH,Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G, Ivanov J, Luo N, Hua G, Martin ML, Farin H, Liu C, Clevers H, Kolesnick R, van den Brink MRM, Hanash AM. Interleukin-22 Is an Intestinal Stem Cell Growth Factor Linking Immunity to Epithelial Regeneration. Nature. 2015; 528:560-4. doi: 10.1038/nature16460.

Deng X, Michaelson D, Tchieu J, Cheng J, Rothenstein D, Feldman R, Lee SG, Fuller J, Haimovitz-Friedman A, Studer L, Powell S, Fuks Z, Hubbard EJ, Kolesnick R.; Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors. PLoS One. 2015; 10:e0127862. doi: 10.1371/journal.pone.0127862. eCollection 2015.

Hla, T and Kolesnick, R.; C16:0-Ceramide Signals Insulin Resistance. Cell Metabolism. 2014; 20:703-705.

Gulbins E, Kolesnick R.; It takes a CAD to kill a tumor cell with a LMP.; Cancer Cell. 2013;24:279-281.

Hua G, Thin TH, Feldman R, Haimovitz–Friedman A, Clevers H, Fuks Z, Kolesnick R. Crypt base columnar stem cells in small intestines of mice are radioresistant. Gastroenterology. 2012;143:1266-76. PMCID: PMC3480544

Rotolo J, Stancevic B, Zhang J, Hua G, Fuller J, Yin X, Haimovitz-Friedman A, Kim K, Qian M, Cardó-Vila M, Fuks Z, Pasqualini R*, Arap W*, Kolesnick R*. Anti-ceramide Antibody Prevents The Radiation GI Syndrome in Mice. J Clin Invest. 2012; 122:1786-90. *Equal co-authors.