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572 News Items found
Bees in a hive
In the Lab
Communal Behavior within Cells Makes Cancers Easier to Target

Findings about proteins called molecular chaperones are shedding new light on possible approaches to cancer treatment.
A chess match
In the Lab
Resistance Is Futile: Targeted Treatment Makes Stubborn Cancers Responsive to Immunotherapy

New research on an experimental drug provides hope for better responses to immunotherapy.
Christine Mayr, MD, PhD
Molecular Biologist Christine Mayr of Sloan Kettering Institute Honored with Prestigious NIH Director’s Pioneer Award

Molecular biologist Christine Mayr, MD, PhD, of Memorial Sloan Kettering’s (MSK) Sloan Kettering Institute (SKI) is one of 12 2016 recipients of the prestigious National Institutes of Health (NIH) Director’s Pioneer Award. Established in 2004, the annual award recognizes and supports individual scientists of exceptional creativity who propose pioneering and highly innovative approaches with the potential to produce an unusually high impact on biomedical or behavioral research.
Memorial Sloan Kettering Researchers Engineer “Micro-Pharmacies” in CAR T Cells to Treat B Cell Lymphomas

There has been much recent excitement about immunotherapy and the use of genetically engineered chimeric antigen receptor (CAR) T cells. Historically, CAR T cell immunotherapy has aimed to boost the immune system by giving immune cells the information they need to better recognize tumor cells as foreign and attack them. New work led by Hans-Guido Wendel, MD, of Memorial Sloan Kettering Cancer Center (MSK), and collaborator Karin Tarte of the University of Rennes, France, illustrates an untapped potential of CAR T cells to act as targeted delivery vehicles that can function as “micro-pharmacies” for precise therapeutic delivery.
Illustration of CAR T cells with conveyor belts leading out of them carrying HVEM protein in tablet form.
In the Lab
New Immunotherapy Approach Turns Cells into “Micro-Pharmacies”

A new immunotherapy approach involves engineering CAR T cells to produce proteins that treat lymphoma.
Alexander Rudensky
In the News
Symposium Held at MSK Honors Alexander Rudensky, Pioneering Immunologist

One of MSK’s leading immunologists turned 60 on Friday, and scientists came to celebrate.
Titan Krios cryo-electron microscope
Feature
Between Two Lenses: An Interview with MSK’s Newest Microscope

Wondering how cryo-electron microscopy will impact medicine? Hear it from the source.
Electronic microscope enlargement of macrophage cell (tinted green)
In the Lab
Origin Story: Finding on Macrophage Development Challenges Long-Held View

A surprising finding challenges long-held dogma about how certain immune cells develop into specialized types in diverse tissues.
Metastatic tumor in the lung, with different colors used to represent the cell nuclei, the blood vessels, and the P-selectin protein.
In the Lab
Hacking Metastasis: Nanotechnology Researchers Find New Way to Target Tumors

A protein in blood vessels that plays a role in cancer metastasis is a promising target for delivering cancer drugs to tumors using nanoparticles.
Dr. Joan Massagué, Sloan Kettering Institute Director received the Pezcoller Foundation-AACR International Award for Cancer Research and was named an AACR fellow at AACR16.
Announcement
News from #AACR16: Targeted Therapy Breakthrough, Improved Survival in Melanoma, and Benefits of Gut Bugs

Long-awaited results of clinical trials testing targeted drugs and immunotherapy combinations were on offer at the annual American Association for Cancer Research (AACR) conference.