Bingbing Wan

Research Fellow



2010 - Fudan University, China, PhD


Chen, Y., Wan, B., Wang, K.C., Cao, F., Yang, Y., Protacio, A., Dou, Y., Chang, H.Y., and Lei, M. (2011). Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. EMBO Reports 12, 797-803.

Huang, J., Gurung, B., Wan, B., Matkar, S., Veniaminova, N.A., Wan, K., Merchant, J.L., Hua, X., and Lei, M. (2012). The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature 482, 542-546.

Huang, J., Wan, B., Wu, L., Yang, Y., Dou, Y., and Lei, M. (2012). Structural insight into the regulation of MOF in the male-specific lethal complex and the non-specific lethal complex. Cell Research 22, 1078-1081.

Sarkar, J., Wan, B., Yin, J., Vallabhaneni, H., Horvath, K., Kulikowicz, T., Bohr, V.A., Zhang, Y., Lei, M., and Liu, Y. (2015). SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates. Nucleic Acids Research 43, 5912-5923.

Wan, B., Tang, T., Upton, H., Shuai, J., Zhou, Y., Li, S., Chen, J., Brunzelle, J.S., Zeng, Z., Collins, K., et al. (2015). The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex. Nature Structural & Molecular Biology 22, 1023-1026.

Wan, B., Yin, J., Horvath, K., Sarkar, J., Chen, Y., Wu, J., Wan, K., Lu, J., Gu, P., Yu, E.Y., et al. (2013). SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres. Cell Reports 4, 861-869.

Yang, Y.W., Flynn, R.A., Chen, Y., Qu, K., Wan, B., Wang, K.C., Lei, M., and Chang, H.Y. (2014). Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife 3, e02046.