Molecular Biology Program
The Xiaolan Zhao Lab
Research

Our lab studies two fundamental aspects of biology that have broad implications for human health. The first research direction examines how cells faithfully duplicate their genomes and repair DNA lesions arising from endogenous and exogenous sources. The second direction focuses on how a protein modifier called SUMO mediates signal transduction, directs the DNA stress response, and dynamically regulates the functions of many proteins. We have implemented a versatile combination of molecular, genetic, biochemical, cell biological, and genomic/proteomic approaches toward answering these questions. Our current work aims to elucidate new underlying principles of the above processes, and reveal how they are integrated with other cellular functions to achieve cell proliferation under various conditions.

Featured News
Publications
People

Xiaolan Zhao, PhD
- Molecular biologist Xiaolan Zhao studies chromosomal organization, genome integrity, DNA replication and repair, dynamic protein modification.
- PhD, Columbia University
- zhaox1@mskcc.org
- Email Address
- 212-639-5582
- Office Phone
Members

- BA, Smith College

- Shanghai Institute of Biochemistry and Cell Biology, PhD

- The University of Sheffield, PhD


Research Associate

Research Scholar

Graduate Student (GSK)

Administrative Assistant II

Research Scholar

Undergraduate Researcher

Research Scholar

Undergraduate Researcher

- BS in Biology, University of California, Berkeley
- PhD Student, Weill Graduate School of Medical Sciences of Cornell University

- BS in Molecular and Cellular Biology, Johns Hopkins University
- PhD Student, Weill Graduate School of Medical Sciences of Cornell University

- B. Tech, Indian Institute of Technology
- PhD Student, Weill Graduate School of Medical Sciences of Cornell University

- BA in Biology/Psychology, Cornell University, Ithaca
- PhD Student, Weill Graduate School of Medical Sciences of Cornell University

- BS in Chemistry-Biochemistry, University of North Carolina at Chapel Hill

- BS in Chemistry, California Institute of Technology
- MD/PhD Student, Weill Graduate School of Medical Sciences of Cornell University

- Diploma in Biology, Justus-Liebig University, Germany
- Ph.D with Dr Karsten Rippe, Graduate Summa cum laude, German Cancer Research Center.
Lab Alumni

Former Graduate Student

Former Graduate Student

Former Research Scholar

Former Graduate Student

Former Graduate Student

Former Research Associate

Former Graduate Student

Former MD/PhD Student

Former Graduate Student

Former Postdoctoral Fellow

Former Research Fellow

Former Postdoctoral Fellow

Former Research Fellow

Former Postdoctoral Fellow

Former Postdoctoral Fellow
Former Postdoctoral Fellow

Former Technician

Former Technician

Former Technician

Former Research Assistant

Former Summer Research Intern

Former Undergraduate Intern

Former Undergraduate Researcher

Former Undergraduate Researcher
Lab Affilations
Achievements
- Bressler Scholar, Alfred W. Bressler Scholar Endowment Fund (2007-2010)
- Research Scholar, American Cancer Society (2012-2016)
- Scholar, Leukemia & Lymphoma Society (2013-2018)
- Discovery of the extensive SUMO-based DNA damage response
- Discovery of the connection between the nuclear pore complex and desumoylation
Read more
- Discovery of the Smc5/6 complex in budding yeast
- Discovery of the essential function of the DNA replication and damage checkpoint
Lab News & Events
Open Positions
Postdoctoral, Graduate Student, & Technician Positions
Positions are available for postdoctoral fellows, graduate students, and technicians in the research group of Dr. Xiaolan Zhao.
Get in Touch
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Lab Head Email
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Office Phone
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Lab Phone
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Lab Fax
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Xiaolan Zhao discloses the following relationships and financial interests:
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Gordon Research Conference
Provision of Services
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.