December 2020
12/11/2020
Presented by Zaki Molvi
“T cells exhibit unexpectedly low discriminatory power and can respond to ultra-low affinity peptide-MHC ligands.”
November 2020
11/13/2020
Presented by Mamadou Bah
“TGF-β suppresses type 2 immunity to cancer.”
11/06/2020
Presented by Keifer Kurtz
“Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.”
October 2020
10/23/2020
Presented by Zita Aretz
“Biogenesis of HLA Ligand Presentation in Immune Cells Upon Activation Reveals Changes in Peptide Length Preference.”
10/16/2020
Presented by Heather Jones
“Metabolic engineering generates a transgene-free safety switch for cell therapy.”
10/09/2020
Presented by Kristen Vogt
“Specific MHC-I Peptides Are Induced Using PROTACs.”
September 2020
9/17/2020
Presented by Leila Peraro
“Engineered off-the-shelf therapeutic T cells resist host immune rejection.”
July 2020
7/10/2020
Presented by Manish Malviya
“ß-cell–mimetic designer cells provide closed-loop glycemic control.”
June 2020
6/26/2020
Presented by Zaki Molvi
“Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection.”
“An insertion unique to SARS-CoV-2 exhibits superantigenic character strengthened by recent mutations.”
May 2020
5/29/2020
Presented by Leila Peraro
“Nitinol thin films functionalized with CAR-T cells for the treatment of solid tumours.”
5/08/2020
Presented by Pedro Silberman
“Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies”
April 2020
4/25/2020
Presented by Kiefer Kurtz
“Long-distance modulation of bystander tumor cells by CD8+ T-cell-secreted IFN-γ.”
4/17/2020
Presented by Kristen Vogt
“An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors.”
4/10/2020
Presented by Zaki Molvi
“Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease.”
4/03/2020
Presented by Megan Dacek
“DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade.”
March 2020
3/20/2020
Presented by Heather Jones
“Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses.”
February 2020
2/14/2020
Presented by Manish Malviya
“Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade”
2/07/2020
Presented by Leila Peraro
“Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1.”
January 2020
1/31/2020
Presented by Megan Dacek
“Targeted deletion of PD-1 in myeloid cells induces antitumor immunity.”
1/24/2020
Presented by Thomas Gardner
“A reversible RNA on-switch that controls gene expression of AAV-delivered therapeutics in vivo.”