Journal Club 2021

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1/29/2021 - presented by Heather Jones

Antigen identification for HLA class I– and HLA class II–restricted T cell receptors using cytokine-capturing antigen-presenting cells.”

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2/05/2021 - presented by Manish Malviya

Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells.”

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2/19/2021 - presented by Megan Dacek

Modeling human adaptive immune responses with tonsil organoids.”

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3/05/2021 - presented by Kristen Vogt

Regulatory T cells engineered with TCR signaling–responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter.”

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3/19/2021 - presented by Keifer Kurtz

Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection.”

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3/05/2021 - presented by Leila Peraro

Engineering Tolerance toward Allogeneic CAR-T Cells by Regulation of MHC Surface Expression with Human Herpes Virus-8 Proteins.”


4/09/2021 - presented by Christopher Bourne

AAV-Mediated In Vivo CAR Gene Therapy for Targeting Human T Cell Leukemia.”

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4/16/2021 - presented by Pedro C. Silberman

Senolytic CAR T cells reverse senescence-associated pathologies.”

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5/21/2021- presented by Zaki Molvi

“CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity.”

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6/04/2021- presented by Zita Aretz

“Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity.”

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7/01/2021- presented by Heather Jones

“TAP dysfunction in dendritic cells enables noncanonical cross-presentation for T cell priming.”

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7/08/2021- presented by Manish Malviya

“Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease.”

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7/15/2021- presented by Kristen Vogt

“Investigation of product derived lymphoma following infusion of piggyBac modified CD19 chimeric antigen receptor T-cells.”

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7/29/2021- presented by Keifer Kurtz

“Gene-engineered exosomes-thermosensitive liposomes hybrid nanovesicles by the blockade of CD47 signal for combined photothermal therapy and cancer immunotherapy.”

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8/12/2021- presented by Chris Bourne

“Pooled screening of CAR T cells identifies non-native signaling domains for next-generation immunotherapies.”

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9/09/2021- presented by Heather Jones

“HLA-E-restricted HIV-1-specific CD8+ T cell responses in natural infection.”

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9/16/21- presented by James Han

“Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade.”

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9/30/21- presented by Pedro Silberman

“Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors.”

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10/14/21- presented by Zita Aretz

“Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.”

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