Journal Club 2022

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6/09/22 - Presented by James Han

“Neoantigen T-Cell Receptor Gene Therapy in Pancreating Cancer.

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6/02/22 - Presented by Patrick Wallisch

The immunostimulatory RNA RN7SL1 enables CAR T cells to enhance autonomous and endogenous immune function.

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5/05/2022 - Presented by Winson Cai

A genome-scale screen for synthetic drivers of T cell proliferation.”

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4/28/2022 - presented by Kristen Vogt  

Sleeping Beauty-engineered CAR T cells achieve antileukemic activity without severe toxicities.”

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“Preclinical Efficacy and Safety of CD19CAR Cytokine-Induced Killer Cells Transfected with Sleeping Beauty Transposon for the treatment of Acute Lymphoblastic Leukemia.”

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4/21/2022 - presented by Zita Aretz

“Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.” 

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4/14/2022 - presented by Shireen Khayat 

“SIRPy-CD47 Interaction Positively Regulates the Activation of Human T Cells in Situation of CHronic Stimulation.”

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3/17/2022 - presented by Zaki Molvi  

“CRISPR activation and interference screens decode stimulation responses in primary human T cells.” 

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Targeting an alternate Wilms’ tumor antigen 1 peptide bypasses immunoproteasome dependency.” 

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2/10/2022 - presented by Pedro Cito Silberman 

“A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control established tumors.” 

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1/13/2022 - presented by Winson Cai 

A human orthogonal IL-2 and IL-2R system enhances

CAR T cell expansion and antitumor activity in amurine model of leukemia.”

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1/06/2022 - presented by Anqi [Nora] Zhou

Natural killer cell receptors regulate responses of HLA-E-restricted T cells.”

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