Cell Biology Program

The Farese & Walther Lab

Research

The Farese & Walther laboratory investigates cellular lipid and energy metabolism, in particular the mechanisms and physiology of neutral lipid synthesis and storage in lipid droplets. More broadly the lab studies the mechanisms how cells regulate the abundance of lipids, how they store lipids to buffer fluctuation in their availability, and how these processes function in membrane biology and cell physiology, and how dysfunction of these pathways leads to diseases, including cancer, metabolic diseases, and neurodegeneration.

Ongoing projects include:

  • Biochemistry and cell biology of lipid droplet formation and degradation
  • Protein targeting to lipid droplets in health and disease
  • Lipid metabolism and lipid droplets in cancer
  • Structural biology of lipid metabolism enzymes
  • Lipid metabolism and neurodegeneration

 

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Research Projects

Publications

People

Tobias Walther
Tobias Walther

Chair, Cell Biology Program; Co-Primary Investigator; HHMI Investigator

Robert Farese
Robert Farese

Co-Primary Investigator

Hamed Abdi

Visiting Investigator (HHMI)

Yohannes Ambaw

Research Associate

Aaron Baublis
Aaron Baublis

Senior Research Technician

Pedro Manuel Carpio Malia
Pedro Manuel Carpio Malia

Research Associate

Yuxuan Han

Research Fellow

Chia-Wei Ken Lee

Research Fellow

Leehyeon Kim
Leehyeon Kim

Research Scholar

Eileen Ortiz
Eileen Ortiz

Assistant to Dr. Walther (Chair) and Dr. Farese

Shubham Singh
Shubham Singh

Research Fellow

Brian Suarez
Brian Suarez

Lab Manager

Wei Chun Tang
Wei Chun Tang

Visiting Investigator

Kun Kenny Wang

Senior Research Scientist

Xiaojun Xiang
Xiaojun Xiang

Research Scholar

Lab Affiliations

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