Most recent articles of our lab:
Palomba R, Isaac E, Spanò R, Piccardi F, McLarney B, Apfelbaum E, Mostafa N, Hsu HT, Grimm J, Decuzzi P. Enhancing Tumor Perfusion and Nanomedicine Delivery by Modulating Vascular Tone with Methyl Palmitate Nanoparticles. ACS Nano. 2026 Aug 4;20(30):21172-21188. doi: 10.1021/acsnano.6c03988. PMID: 42467819; PMCID: PMC13456299.
Encina-Baranda N, Paneque-Yunta RJ, Lopez-Rodriguez J, Pratt EC, Nguyen TN, Grimm J, Lopez-Montes A, Herraiz JL. A tissue-informed deep learning-based method for positron range correction in preclinical [Formula: see text]Ga PET imaging. EJNMMI Phys. 2026 Jun 7;13(1):66. doi: 10.1186/s40658-026-00900-5. PMID: 42251608; PMCID: PMC13287517.
Xing W, Zhou Y, Haedicke K, Wang C, Vazquez-Prada KX, Wu H, Lin Z, Andreou C, Zhang Q, Shang K, Hu R, Kircher M, Ye X, Grimm J, Yang J. Label-free streamlined photoacoustic image guidance facilitates NIR-II photoablation in models of melanoma lung metastases. J Clin Invest. 2026 May 1;136(9):e196095. doi: 10.1172/JCI196095. PMID: 42065242; PMCID: PMC13132385.
Roemhild K, Li Y, Barmin RA, Dadfar SM, Savina E, Lindelauf K, Moeckel D, Rama E, Lemainque T, von Maltzahn F, Thoröe-Boveleth S, Pola R, Etrych T, Knuechel-Clarke R, Boor P, Kraus T, Schulz V, Grimm J, Kiessling F, von Stillfried S, Pallares RM, Lammers T. Effect of clinically relevant iron oxide nanoparticles on macrophage polarization, tumor growth and tumor microenvironment modulation. J Control Release. 2026 Apr 10;392:114726. doi: 10.1016/j.jconrel.2026.114726. Epub 2026 Feb 13. PMID: 41692043; PMCID: PMC13450206.
Tamura R, Grimm J. Syntheses, Biological and Preclinical Evaluations, and Nanoparticle Formulations of the ROS-Activatable Prodrugs of Doxazolidine for Drug-Resistant Cancer Therapy. Mol Pharm. 2026 Jan 5;23(1):319-328. doi: 10.1021/acs.molpharmaceut.5c01101. Epub 2025 Dec 9. PMID: 41366837; PMCID: PMC12879253.
Sonay AY, Apfelbaum E, Larney BEM, Grimm J. Phosphatidylserine exposure and plasma membrane perforation as ferroptotic signatures for in vivo imaging. Npj Imaging. 2025 Oct 6;3(1):48. doi: 10.1038/s44303-025-00110-1. PMID: 41053337; PMCID: PMC12500960.
Pratt EC, Shaffer TM, Bauer D, Lewis JS, Grimm J. Radiances of Cerenkov-Emitting Radionuclides on the In Vivo Imaging System. J Nucl Med. 2025 May 1;66(5):817-821. doi: 10.2967/jnumed.124.268806. PMID: 40081951; PMCID: PMC12051767.
Skubal M, Larney BM, Phung NB, Desmaras JC, Dozic AV, Volpe A, Ogirala A, Machado CL, Djibankov J, Ponomarev V, Grimm J. Vascularized tumor on a microfluidic chip to study mechanisms promoting tumor neovascularization and vascular targeted therapies. Theranostics. 2025 Jan 1;15(3):766-783. doi: 10.7150/thno.95334. PMID: 39776800; PMCID: PMC11700857.
Grimm J, Kiessling F, Pichler BJ. Quo Vadis,Molecular Imaging? J Nucl Med. 2020 Oct;61(10):1428-1434. doi: 10.2967/jnumed.120.241984. Epub 2020 Aug 28. PMID: 32859706.
Pratt EC, Isaac E, Stater EP, Yang G, Ouerfelli O, Pillarsetty N, Grimm J. Synthesis of the PET Tracer 124I-Trametinib for MAPK/ERK Kinase Distribution and Resistance Monitoring. J Nucl Med. 2020 Dec;61(12):1845-1850. doi: 10.2967/jnumed.120.241901. Epub 2020 May 22. PMID: 32444378.
Haedicke K, Agemy L, Omar M, Berezhnoi A, Roberts S, Longo-Machado C, Skubal M, Nagar K, Hsu HT, Kim K, Reiner T, Coleman J, Ntziachristos V, Scherz A, Grimm J. High-resolution optoacoustic imaging of tissue responses to vascular-targeted therapies. Nat Biomed Eng. 2020 Mar;4(3):286-297. doi: 10.1038/s41551-020-0527-8. Epub 2020 Mar 12. PMID: 32165736; PMCID: PMC7153756.
Mueller JJ, Dauer LT, Murali R, Iasonos A, Pandit-Taskar N, Abu-Rustum NR, Grimm J. Positron Lymphography via Intracervical 18F-FDG Injection for Presurgical Lymphatic Mapping in Cervical and Endometrial Malignancies. J Nucl Med. 2020 Aug;61(8):1123-1130. doi: 10.2967/jnumed.119.230714. Epub 2020 Jan 10. PMID: 31924717; PMCID: PMC7413230.
Alvim R, Nagar K, Das S, Lebdai S, Wong N, Somma A, Hughes C, Thomas J, Monette S, Scherz A, Kim K, Grimm J, Coleman JA. Positron Emission Tomography/Computed Tomography with Gallium-68-labeled Prostate-specific Membrane Antigen Detects Relapse After Vascular-targeted Photodynamic Therapy in a Prostate Cancer Model. Eur Urol Focus. 2019 Jun 18:S2405-4569(19)30163-4. doi: 10.1016/j.euf.2019.06.008. Epub ahead of print. PMID: 31227464; PMCID: PMC7032651.