Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma. 2024. Chen, Y, Iyer, S, Hsieh, D, Li, B, Elias, H, Wang, T, Li, J, Ganbold, M, Lien, M, Peng, Y, Xie X, Jayewickreme, C, van den Brink, M, Brady, S, Lim, S, Parada, LF. 2024, Nature, https://doi.org/10.1038/s41586-024-08224-z.Glioblastoma functional heterogeneity and enrichment of cancer stem cells with tumor recurrence. 2024. Xie XP, Ganbold M, Li J, Lien M, Chipman ME, Wang T, Jayewickreme CD, Pedraza AM, Bale T, Tabar V, Brennan C, Sun D, Sharma R, Parada LF. 2024, Neuron, PMID: 39510072.Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors. 2024. Sait SF, Tang KH, Angus SP, Brown R, Sun D, Xie X, Iltis C, Lien M, D Socci N, Bale TA, Davis C, Dixon SAH, Zhang C, Wade Clapp D, Neel BG, Parada LF. 2024, Proc Natl Acad Sci U S A, PMID: 39793045; PMCID: PMC11725864.Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy. 2022. Xie XP, Laks DR, Sun D, Ganbold M, Wang Z, Pedraza AM, Bale T, Tabar V, Brennan C, Zhou X, Parada LF. 2022, Dev Cell, PMCID: PMC8820651.Stem-like cells drive NF1-associated MPNST functional heterogeneity and relapse after chemotherapy. 2021. Sun D, Xie X, Wang Z, Sait S, Iyer S, Chen Y, Brown R, Laks D, Chipman M, and Parada L. 2021, Cell Stem Cell, PMCID: PMC8349880. Book traversal links for The Luis Parada Lab Previous Featured News Next Open Positions