Marilyn Resh: Publications

Marilyn Resh: Publications


Petrova, E., Rios-Esteves, J., Ouerfelli, O., Glickman, J.F. and Resh, M.D. (2013) Inhibitors of Hedgehog Acyltransferase Block Sonic Hedgehog Signaling. Nature Chem. Biol. 9: 247-249. **Highlighted in News and Views, Ibid pp217-8**

Resh, M.D. (2013) Covalent Lipid Modifications of Proteins. Curr. Biol. 23:R431-R435.

Rios-Esteves, J. and Resh, M.D. (2013) Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins. Cell Reports 4: 1072-1081.

Petrova, E., Matevossian, A., and Resh, M.D. (2015) Hedgehog Acyltransferase as a target for inhibiting pancreatic cancer cell growth. Oncogene 34, 263-268. First e-published 2014 Jan 27. doi: 10.1038/onc.2013.575

Callier, P. Calvel, P., Matevossian, A., Makrythanasis, P., Kurosaka, H., Vannier,A., Thauvin-Robinet, C., Bernard, P., Borel, C., Mazaud-Guittot, S., Rolland, A., desdoits-lethimonier, C., Guipponi, M., Zimmermann, C., Kuhne, F., Conne, B., Santoni, F., Lambert, S., Huet, F., Mugneret, F., Jaruzelska, J., Faivre, L., Wilhelm, D., Jégou, B., Trainor, P.A., Resh, M.D., Antonarakis, S.E., and Nef, S. (2014) Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling. PLoS Genet., DOI.1371/ journal.pgen.1004340.

Rios-Esteves, J., Haugen, B., and Resh, M.D. (2014) Identification of key residues and regions important for Porcupine-mediated Wnt acylation. J. Biol. Chem. 289: 17009-17019.

Matevossian, A. and Resh, M.D. (2015) Membrane Topology of Hedgehog Acyltransferase. J. Biol. Chem. 290: 2235-2243.

Matevossian, A. and Resh, M.D. (2015) Hedgehog Acyltransferase as a target in estrogen receptor positive, HER2 amplified, and tamoxifen resistant breast cancer cells. Mol. Cancer 14:72 doi:10.1186/s12943-015-0345-x.

Resh, M.D. (2016) Lipid Modification of Proteins, in Biochemistry of Lipids, Lipoproteins and Membranes (Ridgway, N.D. and McLeod, R.S., Elsevier) Chapter 13, pp 391-414.

Resh, M.D. (2016) Fatty Acylation of Proteins: The Long and the Short of it. Prog. Lipid Res. 63: 120-131.

Resh, M.D. (2017) HO-2 Pockets Myristoylated Gag. Cell Host & Microbe 21:131-133.

Resh, M.D. (2017) Palmitoylation of Proteins in Cancer. Biochem. Soc. Trans. 45:409-416.

Asciolla, J.J., Miele, M.M., Hendrickson, R.C., and Resh, M.D. (2017) An in vitro fatty acylation assay reveals a mechanism for Wnt recognition by the acyltransferase Porcupine. J. Biol. Chem., 292:13507-13513.