The Marilyn Resh Lab: Publications

Visit PubMed for a full listing of Marilyn Resh’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Petrova, E., Rios-Esteves, J., Ouerfelli, O., Glickman, J.F. and Resh, M.D. (2013) Inhibitors of Hedgehog Acyltransferase Block Sonic Hedgehog Signaling. Nature Chem. Biol. 9: 247-249. **Highlighted in News and Views, Ibid pp217-8**

Resh, M.D. (2013) Covalent Lipid Modifications of Proteins. Curr. Biol. 23:R431-R435.

Rios-Esteves, J. and Resh, M.D. (2013) Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins. Cell Reports 4: 1072-1081.

Petrova, E., Matevossian, A., and Resh, M.D. (2015) Hedgehog Acyltransferase as a target for inhibiting pancreatic cancer cell growth. Oncogene 34, 263-268. First e-published 2014 Jan 27. doi: 10.1038/onc.2013.575

Callier, P. Calvel, P., Matevossian, A., Makrythanasis, P., Kurosaka, H., Vannier,A., Thauvin-Robinet, C., Bernard, P., Borel, C., Mazaud-Guittot, S., Rolland, A., desdoits-lethimonier, C., Guipponi, M., Zimmermann, C., Kuhne, F., Conne, B., Santoni, F., Lambert, S., Huet, F., Mugneret, F., Jaruzelska, J., Faivre, L., Wilhelm, D., Jégou, B., Trainor, P.A., Resh, M.D., Antonarakis, S.E., and Nef, S. (2014) Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling. PLoS Genet., DOI.1371/ journal.pgen.1004340.

Rios-Esteves, J., Haugen, B., and Resh, M.D. (2014) Identification of key residues and regions important for Porcupine-mediated Wnt acylation. J. Biol. Chem. 289: 17009-17019.

Matevossian, A. and Resh, M.D. (2015) Membrane Topology of Hedgehog Acyltransferase. J. Biol. Chem. 290: 2235-2243.

Matevossian, A. and Resh, M.D. (2015) Hedgehog Acyltransferase as a target in estrogen receptor positive, HER2 amplified, and tamoxifen resistant breast cancer cells. Mol. Cancer 14:72 doi:10.1186/s12943-015-0345-x.

Resh, M.D. (2016) Lipid Modification of Proteins, in Biochemistry of Lipids, Lipoproteins and Membranes (Ridgway, N.D. and McLeod, R.S., Elsevier) Chapter 13, pp 391-414.

Resh, M.D. (2016) Fatty Acylation of Proteins: The Long and the Short of it. Prog. Lipid Res. 63: 120-131.

Resh, M.D. (2017) HO-2 Pockets Myristoylated Gag. Cell Host & Microbe 21:131-133.

Resh, M.D. (2017) Palmitoylation of Proteins in Cancer. Biochem. Soc. Trans. 45:409-416.

Asciolla, J.J., Miele, M.M., Hendrickson, R.C., and Resh, M.D. (2017) An in vitro fatty acylation assay reveals a mechanism for Wnt recognition by the acyltransferase Porcupine. J. Biol. Chem., 292:13507-13513.