Adina R. Schonbrun, PhD

Adina R. Schonbrun, PhD

Adina Schonbrun


Kinetic Mechanism and Substrate Specificity of Hedgehog Acyltransferase

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BA, Yeshiva University


  • GSK Grayer Fellowship  (2019-2020)
  • American Heart Association Predoctoral Fellowship (2020-2022)


Schonbrun AR, Resh MD. (2022) Hedgehog acyltransferase catalyzes a random sequential reaction and utilizes multiple fatty acyl-CoA substrates. J Biol Chem. 298 (10).

Schonbrun AR, Resh MD. A Direct in vitro Fatty Acylation Assay for Hedgehog Acyltransferase. Bio Protoc. 2022 Dec 20;12(24):e4573. doi: 10.21769/BioProtoc.4573. PMID: 36618094; PMCID: PMC9797357.

Banerjee, S. J., Schonbrun, A., Eizadshenass, S., Benji, S., Cantor, Y. T., Eliach, L., Lubin, M., Narrowe, Z., Purow, J., Shulman, B., Wiener, L., & Steinhauer, J. (2021). iPLA2-VIA is required for healthy aging of neurons, muscle, and the female germline in Drosophila melanogaster. PloS one16(9), e0256738.

Mehla, J., R. Ernst, R MooreA. Wakschlag, M. K. Marquis, S. V. Ambudkar, and J. Golin. “Evidence for a Molecular Diode-based Mechanism in a Multi-specific ABC Exporter: Ser-1368 as a Gatekeeping Residue in the Yeast Multidrug Transporter Pdr5.” Journal of Biological Chemistry 289.38 (2014): 26597-6606. 

Downes, M. T., J. Mehla, N. Ananthaswamy, A. Wakschlag, M. Lamonde, E. Dine, S. V. Ambudkar, and J. Golin. “The Transmission Interface of the Saccharomyces Cerevisiae Multidrug Transporter Pdr5: Val-656 Located in Intracellular Loop 2 Plays a Major Role in Drug Resistance.” Antimicrobial Agents and Chemotherapy 57.2 (2013): 1025-034.