Jake Bonner

Former Graduate Student
The Xiaolan Zhao Lab
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Jake Bonner

Former Graduate Student
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Jake Bonner

Education

BS in Chemistry-Biochemistry, University of North Carolina at Chapel Hill; PhD, Weill Cornell Graduate School of Medical Sciences

Current Position
Senior Scientist I, Altos Labs

Publications

Li S, Bonner JN, Wan B, So S, Summers A, Gonzalez L, Xue X, Zhao X. Esc2 orchestrates substrate-specific sumoylation by acting as a SUMO E2 cofactor in genome maintenance. Genes Dev. 2021 Feb 1;35(3-4):261-272. doi: 10.1101/gad.344739.120. Epub 2021 Jan 14. PMID: 33446573; PMCID: PMC7849368.

Bonner JN, Zhao X. Replication-Associated Recombinational Repair: Lessons from Budding Yeast. Genes (Basel). 2016 Aug 17;7(8). doi: 10.3390/genes7080048. Review. PubMed [PMID: 27548223]; PubMed Central PMCID: PMC4999836.

Bonner JN, Choi K, Xue X, Torres NP, Szakal B, Wei L, Wan B, Arter M, Matos J, Sung P, Brown GW, Branzei D, Zhao X. Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates. Cell Rep. 2016 Jul 12;16(2):368-378. doi: 10.1016/j.celrep.2016.06.015. Epub 2016 Jun 30. PubMed [PMID: 27373152]; PubMed Central PMCID: PMC5051638.

Xue X, Papusha A, Choi K, Bonner JN, Kumar S, Niu H, Kaur H, Zheng XF, Donnianni RA, Lu L, Lichten M, Zhao X, Ira G, Sung P. Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1. Genes Dev. 2016 Mar 15;30(6):687-99. doi: 10.1101/gad.276139.115. Epub 2016 Mar 10. PMID: 26966246; PMCID: PMC4803054.

Xue, X., Choi, K., Bonner, J.N., Szakal, B., Chen, Y.H., Papusha, A., Saro, D., Niu, H., Ira, G., Branzei, D., Sung P., Zhao, X. (2015). Selective modulation of the functions of a conserved DNA motor by a histone fold complex. Genes & Development 29, 1000-1005.

Xue, X., Choi, K., Bonner, J., Chiba, T., Kwon, Y., Xu, Y., Sanchez, H., Wyman, C., Niu, H., Zhao, X., Sung, P. (2014). Restriction of replication fork regression activities by a conserved SMC complex. Molecular Cell 56, 436-445.

Houck SA, Ren HY, Madden VJ, Bonner JN, Conlin MP, Janovick JA, Conn PM, Cyr DM, (2014). Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHR. Molecular Cell 54, 166-79.