Thane Than, PhD

Former Research Fellow

Thane Than, PhD

Former Research Fellow
Thane Than

Start Year


End Year



The University of Sheffield, PhD

Current Position
Civil Servant, Her Majesty’s Civil Service, UK


Kaushik A, Than T, Petela NJ, Voulgaris M, Percival C, Daniels P, Rafferty JB, Nasmyth KA, Hu B. (2023). Conformational dynamics of cohesin/Scc2 loading complex are regulated by Smc3 acetylation and ATP binding. Nat Commun. 14:5929.

Chang JT, Li S, Beckwitt E, Than T, Haluska C, Chandanani J, O’Donnell ME, Zhao X*, Liu S* (*co-corresponding authors). (2022). Smc5/6’s multi-faceted DNA binding capacities stabilize branched DNA structuresNat Commun 13:7179

Yu Y, Li S, Ser Z, Kuang H, Than T, Guan D, Zhao X, Patel DJ. (2022). Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes. Proc Natl Acad Sci U S A. 119:e2202799119.

Bürmann, F., Lee, B., Than, T., Sinn, L., O’Reilly, F., Yatskevich, S., Rappsilber, J., Hu, B., Nasmyth, K. and Löwe, J. (2019). A folded conformation of MukBEF and cohesin. Nature Structural & Molecular Biology. 26:227-236.