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Physician-scientist Alex Kentsis
In the Lab
Research points to the role of a protein called MYB, which has long been known to play a role in cancer.
Direna Alonso Curbelo
The insights lay the groundwork for earlier diagnosis and better treatment of the disease.
MSK immunologist Ming Li
Scientists have long known that cancer cells and immune cells have an uncommon hunger for glucose but haven’t understood why. A new study offers an answer.
Francisco Sánchez-Rivera
During World War II, US factories famously converted their operations to support the war effort. COVID-19 instigated something similar among cancer scientists.
Human metastatic melanoma cells in a lymph node. ENPP1, a protein involved in immune evasion, is shown in green.
The research identifies a protein called ENPP1 as a potential drug target in the treatment of advanced cancers with chromosome instability.
Dana Pe'er, Chair of the Computational and Systems Biology Program at the Sloan Kettering Institute
Take a look back at some of the biggest cancer science stories from this past year.
Structure of an intermediate during the homologous recombination reaction.
The high-resolution views provided by cryo-electron microscopy are helping scientists learn how proteins and DNA collaborate to repair broken DNA.
Nadeem Riaz (left) and Jorge Reis-Filho (right)
Human data and results from mouse experiments suggest that people with BRCA2 mutations may respond well to immunotherapy drugs.
Systems biologist Joao Xavier in his lab
Finding
MSK researchers have shown for the first time that the concentration of different types of immune cells in the blood changes in relation to the presence of different bacterial strains in the gut.
SKI cell biologists Junmei Yi and Xuejun Jiang
In the Lab
Cancers with certain mutations are vulnerable to ferroptosis, a form of iron-dependent cell death.