In the Huse lab, we combine single cell imaging approaches with synthetic peptide chemistry and protein design in order to study signal transduction and cytoskeletal dynamics in lymphocytes.
- Le Floc’h, A. Tanaka, Y., Bantilan, N. S., Voisinne, G., Altan-Bonnet, G., Fukui, Y., and Huse, M. (2013). Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse. J Exp Med. 210, 2721-2737.
- Quann EJ, Liu X, Altan-Bonnet G, Huse, M. A Cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells. Nat Immunol. 2011 May 22;12(7):647-54. doi: 10.1038/ni.2033.
- Searle Scholar Award (2008)
- Kavli Fellow (2010)