Center for Molecular Imaging & Bioengineering

Citation: Keshari, K., Heller, D., Boltyanskiy, R., Hricak, H., Magaldi, T., Overholtzer, M. Engineering focusing on cancer. Cancer Cell, (42)7, 1138-1141
The Center of Molecular Imaging and Bioengineering leads a transformative field that fuses modern bioengineering and cancer engineering concepts with sound biological principles. The Center serves as an incubator, allowing researchers to rapidly pursue these leads and build novel tools and technology that address oncology’s most pressing needs. Keshari, K. R., Heller, D. A., Boltyanskiy, R., Hricak, H., Magaldi, T., & Overholtzer, M. (2024). Engineering focusing on cancer. Cancer Cell, 42(7), 1138–1141.

About the Center

The mission of the Center for Molecular Imaging and Bioengineering (CMIB) is to integrate novel molecular imaging methods and state-of-the-art bioengineering tools to revolutionize the way Memorial Sloan Kettering Cancer Center (MSK) approaches cancer research. In uniting these transformational fields, we aim to answer fundamental questions in cancer biology and rapidly translate preclinical discovery into clinical application — ultimately improving cancer prevention, detection, and treatment.

The center is founded on the principle of multidisciplinary translational research and supports faculty from diverse areas pursuing technology-based methods. CMIB encourages collaborative integration across the cutting-edge research environment at MSK, empowering scientists and clinicians alike by providing them with the tools necessary to pursue their most challenging ideas.

  • Colleen Maher, Senior Program Manager
  • Kimberly Hubbard, Senior Project Coordinator

Featured News

Center of Molecular Engineering and Bioengineering faculty members attended Cancer Engineering Workshop in Washington, D.C.
Center for Molecular Imaging and Bioengineering faculty members attended the the National Academies of Sciences, Engineering, and Medicine  Cancer Engineering Workshop in Washington, D.C.

 

 

Members

Under the leadership of biochemist and bioengineer Kayvan R. Keshari, CMIB promotes the expansion and application of technological capabilities, creating a new approach to cancer research and propelling MSK to the forefront of cancer engineering.

To achieve our goals, CMIB fosters deep ties between technology experts and faculty by establishing multidisciplinary teams with diverse but interrelated projects directed toward the common goal of applying molecular imaging and engineering principles to transformative questions — and unmet patient needs — in oncology.

We invite faculty working in cancer biology, medicine, chemistry, developmental biology, physics, radiochemistry, immunology, genomics, pharmacology, computational oncology, and engineering to join our center. To reach out for collaboration opportunities or for more information about the CMIB, contact us at [email protected].

Internal Advisory Committee

Our internal advisory committee comprises the following MSK leaders:
 

Jason S. Lewis
Deputy Director, Sloan Kettering Institute – Office of Science Education and Training (OSET); Emily Tow Chair in Oncology
Pictured: Anna-Katerina Hadjantonakis
Chair, Developmental Biology Program, SKI; Alfred P. Sloan Chair
Pictured: Michael Overholtzer
Dean, Gerstner Sloan Kettering Graduate School
Daniel Heller
Member, Molecular Pharmacology Program, SKI
Hedvig Hricak, MD
Emeritus
  • Michael Berger
  • Nai-Kong Cheung
  • Karuna Ganesh
  • Benjamin Greenbaum
  • Jan Grimm
  • Richard Hite
  • Danwei Huangfu
  • Morgan Huse
  • Kayvan Keshari
  • Michael Kharas
  • Christopher Klebanoff
  • Christina Leslie
  • Ross Levine
  • Christopher Lima
  • Stephen Long
  • Scott Lowe
  • Joan Massague
  • Quaid Morris
  • Thomas Norman
  • Dana Pe’er
  • Justin Perry
  • Alexandros Pertsinidis
  • Milind Rajadhyaksha
  • Ed Reznik
  • Charles Rudin
  • David Scheinberg
  • Nikolaus Schultz
  • Sohrab Shah
  • Viviane Tabar
  • Tuomas Tammela
  • Wesley Tansey
  • Andrea Ventura
  • Joao Xavier

Research

At the Center for Molecular Imaging and Bioengineering we develop and support novel technologies aimed at transforming capabilities in cancer research and care. We build tools and create methods that push the current limits of cancer imaging and detection. In additional to hands-on development, we financially support pilot grants for interdisciplinary research projects focused on cancer-specific bioengineering. We bring together engineers, physicists, cancer biologists and clinicians to create innovative solutions that both leverage currently strong research programs at MSK and forge into the less developed research directions. In doing so, we hope to strengthen the existing core facilities with cutting edge technologies, bring novel bioengineering tools to the clinic and invite more cancer engineers to join the MSK research community.  

Outreach

CMIB is involved in numerous outreach programs that aim to create opportunities for education, collaboration and training. We support the Cancer Engineering seminar series that brings world-renown speakers who share insights from their work on novel developments in cancer-focused bioengineering. We organize the Cancer Engineering Research in Progress seminar series that offers students and postdocs opportunities to present their work, get suggestions from peers and identify ideas for collaboration. Our summer programs for college students offer unique research opportunities for young scientists that allow them to develop novel skills and gain experiences that help them decide the next steps in their careers. Overall, CMIB outreach brings together interdisciplinary scientists at different stages of training and aims to create a vibrant, collaborative cancer engineering community.

Awards

To disseminate and cultivate imaging and engineering sciences into cancer biology research at MSK, CMIB sponsors pilot research grants and has established a technology fund to support lab heads and core facilities with acquiring advanced tools and technological resources.

 

Justin Perry, PhD
2025 CMIB Technology Pilot Research Grant
Justin Perry, PhD
“Targeting macrophage degradation of apoptotic tumor cells to boost innate immunity against cancer” 

 

Jan Grimm
2025 CMIB Trainee Award
PI: Jan Grimm, PhD and Trainee Elisa Chazeau PhD 
“A Universal Theranostic Agent”

Education

GSK students in the Cancer Engineering Program are using a tabletop MRI machine to explore a number of magnetic resonance phenomena, particularly magnetic relaxation properties.
GSK students in the Cancer Engineering Program are using a tabletop MRI machine to explore a number of magnetic resonance phenomena, particularly magnetic relaxation properties.

CMIB is committed to training young scientists in the field of cancer engineering through numerous programs. We partner to provide opportunities to undergraduate students to experience what cutting edge cancer research is like with summer programs. CMIB works with graduate students in the GSK Cancer Engineering PhD program and provides fellowships to students at other institutions. We also participate in initiatives to bring cancer engineering opportunities to young scientists in underrepresented groups. 

The new Gerstner Sloan Kettering (GSK) PhD in Cancer Engineering is a program designed to train the next generation of molecular imaging and bioengineering tool makers fully versed in cancer biology. The first class will matriculate in 2024.

Funded by a National Cancer Institute research training grant (T32 CA254875), the Molecular Imaging in Cancer Biology (MICB) Training Program — led by Jason Lewis, Hedvig Hricak, and Michael Overholtzer — aims to train the next generation of basic scientists to develop cutting-edge diagnostic, prognostic, and therapeutic tools and translate novel molecular imaging methods, technologies, and platforms to better understand human cancer biology. The ultimate goal of the program is to enable trainees to advance the diagnosis, treatment, and management of cancer.

Learn more about our T32 Molecular Imaging in Cancer Biology current fellows.

The City College of New York (CCNY) and Memorial Sloan Kettering Cancer Center (MSK) Partnership is a National Cancer Institute–funded initiative based on mutual cancer research and training objectives in several key areas, including but not limited to basic and applied science, health disparities and cancer burden in underrepresented populations, career development for underrepresented students at all levels, and the reduction of cancer impact in medically underserved communities.

The Engineering Summer Program (ESP) is designed to bring together undergraduate rising sophomores, juniors, and seniors interested in engineering and biomedicine for a 10-week summer research experience in labs at Memorial Sloan Kettering Cancer Center or Weill Cornell Medicine. Applicants must have a background in engineering, physical sciences, computational, or related fields.

Featured Publications