The focus of my work is to use transgenic human embryonic stem cells (hESCs) that express GFP under promoters that are specific to midbrain dopamine (mDA) neurons in order to purify, characterize, and graft these cells in a mouse model of Parkinson’s disease. I am also working with the Rutishauser lab to overexpress polysialic acid neural cell adhesion molecule (PSA-NCAM) in grafted hESC-derived mDA neurons to increase their integration into the host CNS. Additionally, I am a co-host and producer of THE Stem Cell Podcast - the official podcast of the International Society for Stem Cell Research. Together with Dr. Christopher Fasano we interview stem cell scientists and discuss recent advances in the field.
Yosif Martin Ganat, PhD
Postdoctoral Fellow - currently: Research Investigator, Arvinas,, New Haven, CT
The focus of my work is to use transgenic human embryonic stem cells (hESCs) that express GFP under promoters that are specific to midbrain dopamine (mDA) neurons in order to purify, characterize, and graft these cells in a mouse model of Parkinson’s disease. I am also working with the Rutishauser lab to overexpress polysialic acid neural cell adhesion molecule (PSA-NCAM) in grafted hESC-derived mDA neurons to increase their integration into the host CNS. Additionally, I am a co-host and producer of THE Stem Cell Podcast - the official podcast of the International Society for Stem Cell Research. Together with Dr. Christopher Fasano we interview stem cell scientists and discuss recent advances in the field.