Developmental Biology Program

The Lorenz Studer Lab

Research

Pictured: Dr. Lorenz Studer
Lorenz Studer, MD
Director, Center for Stem Cell Biology

Our laboratory aims at exploiting recent advances in stem cell biology to develop radically new therapies for degenerative disease and cancer. The main focus in the lab is on the biology and application of human embryonic stem (ES) and human induced pluripotent (iPS) cells. Pluripotent stem cells can provide a truly unlimited source for deriving therapeutically relevant cell types for applications in human disease modeling or regenerative medicine.

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Research Projects

Lorenz Studer Lab

Publications Highlights

Ciceri G, Baggiolini A, Cho HS, Kshirsagar M, Benito-Kwiecinski S, Walsh RM, Aromolaran KA, Gonzalez-Hernandez AJ, Munguba H, Koo SY, Xu N, Sevilla KJ, Goldstein PA, Levitz J, Leslie CS, Koche RP, Studer L. An epigenetic barrier sets the timing of human neuronal maturation. Nature. 2024 Jan 31. doi: 10.1038/s41586-023-06984-8. Online ahead of print.PMID: 38297124

Hergenreder E, Minotti AP, Zorina Y, Oberst P, Zhao Z, Munguba H, Calder EL, Baggiolini A, Walsh RM, Liston C, Levitz J, Garippa R, Chen S, Ciceri G, Studer L. Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons. Nat Biotechnol. 2024 Jan 2. doi: 10.1038/s41587-023-02031-z. Online ahead of print. PMID: 38168993

Fan Y, Hackland J, Baggiolini A, Hung LY, Zhao H, Zumbo P, Oberst P, Minotti AP, Hergenreder E, Najjar S, Huang Z, Cruz NM, Zhong A, Sidharta M, Zhou T, de Stanchina E, Betel D, White RM, Gershon M, Margolis KG, Studer L. hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease. Cell Stem Cell. 2023 Mar 2;30(3):264-282.e9. doi: 10.1016/j.stem.2023.02.003.PMID: 36868194 

Yang L, Kim TW, Han Y, Nair MS, Harschnitz O, Zhu J, Wang P, Koo SY, Lacko LA, Chandar V, Bram Y, Zhang T, Zhang W, He F, Pan C, Wu J, Huang Y, Evans T, van der Valk P, Titulaer MJ, Spoor JKH, Furler O’Brien RL, Bugiani M, D J Van de Berg W, Schwartz RE, Ho DD, Studer L, Chen S. SARS-CoV-2 infection causes dopaminergic neuron senescence. Cell Stem Cell. 2024 Feb 1;31(2):196-211.e6. doi: 10.1016/j.stem.2023.12.012. Epub 2024 Jan 17.PMID: 38237586 

Giacomelli E, Vahsen BF, Calder EL, Xu Y, Scaber J, Gray E, Dafinca R, Talbot K, Studer L. Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation. Cell Stem Cell. 2022 Jan 6;29(1):11-35. doi: 10.1016/j.stem.2021.12.008.PMID: 34995492

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People

Pictured: Dr. Lorenz Studer

Lorenz Studer, MD

Director, Center for Stem Cell Biology

  • The Studer laboratory investigates human stem cells as tools to understand normal and pathological development in the nervous system and to develop cell-based strategies for regenerative medicine.
  • MD, Universitat Bern
[email protected]
Email Address
212-639-6126
Office Phone

Members

Lorenz Studer
Lorenz Studer

Member

Marta Lisi
Marta Lisi

Lab Manager

Alex Henderson
Alex Henderson

Program Manager

Silvia K. Benito Kwiecinski
Silvia Benito Kwiecinski

Research Fellow

Vittoria Bocchi
Vittoria Bocchi

Research Associate

Gabriele Ciceri, Ph.D.
Gabriele Ciceri

Senior Research Scientist

Elisa Giacomelli
Elisa Giacomelli

Research Associate

James Hackland
James Hackland

Senior Research Scientist

Luz Jubierre

Senior Research Scientist

Johannes Jungverdorben, PhD
Johannes Jungverdorben

Senior Research Scientist

Noopur Khobrekar
Noopur Khobrekar

Research Fellow

Dylan Ritter

Research Scholar

Nathalie Saurat, PhD
Nathalie Saurat

Senior Research Scientist

Ryan Walsh, PhD
Ryan Walsh

Senior Research Scientist

Leslie Weber

Research Associate

Donghe Yang
Donghe Yang

Research Fellow

Zhe Yang
Zhe Yang, PhD

Research Fellow - NYSTEM Training Award at the CSCB

Miguel Chavez Pachas

Graduate Student

Alessandro Evangelisti
Alessandro Evangelisti

Graduate Student

Andrew Minotti
Andrew Minotti

Graduate Student

Maliha Rahman

Graduate Student

Berkiye Sonustun
Berkiye Sonustun

Graduate Student, Rita L. Montalcini Fellow

Xiaoyi "Claire" Wang

Graduate Student

Nan Xu
Nan Xu

Graduate Student

Jalwa Afroz

Research Technician

Param Amin
Param Amin

Research Technician

Kaylin Sevilla Lopez
Kaylin Sevilla Lopez

Research Technician

Trisha Sikder

Research Technician

Danaysy Frias
Danaysy Frias

Senior Administrative Assistant

Lab Alumni
Yujie Fan
Yujie Fan

Graduate Student

Samantha Phillips
Samantha Phillips

Graduate Student

Angela Pepe-Caprio
Angela Pepe-Caprio

Lab Manager

Elizabeth L Calder, PhD
Elizabeth L Calder, PhD

Senior Research Scientist

Arianna Baggiolini
Arianna Baggiolini, PhD

Research Fellow

Isabelle de Luzy
Isabelle de Luzy, PhD

Research Fellow

Oliver Härschnitz
Oliver Härschnitz, MD, PhD

Research Associate - NYSTEM Training Award at the CSCB

Emiliano Hergenreder
Emiliano Hergenreder

Graduate Student

Marietta Saldias Montivero

Lab Technician - currently: MD/PhD student

Daniela Cornacchia, PhD
Daniela Cornacchia, PhD

Postdoctoral Fellow

TaeWan Kim, PhD
TaeWan Kim

Senior Research Scientist

Sudha Guttikonda
Sudha Guttikonda

Graduate Student

Polina Oberst, PhD
Polina Oberst

Research Associate

Jason Tchieu
Jason Tchieu

Postdoctoral Fellow - currently: Assistant Professor, Cincinnati Children’s Hospital, Cincinnati, OH

Scott J. Callahan
Scott J. Callahan

Vice President, Director of Medical Strategy at Havas Health & You, New York, NY

Gustav Cederquist
Gustav Cederquist

Graduate Student – currently: Resident in Radiation Oncology, Memorial Sloan Kettering Cancer Center

Eveline Gutzwiller
Eveline Gutzwiller

Postdoctoral Fellow - currently: Neurology resident, Mount Sinai Medical School, New York, NY

Nadja Zeltner, PhD
Nadja Zeltner

Postdoctoral fellow – currently, Assistant Professor, University of Georgia

Faranak Fattahi, MS
Faranak Fattahi

Graduate Student - currently, Sandler Faculty Fellow, UCSF

Michelle Vincendeau

Postdoctoral Fellow – currently: Group leader, Helmholtz Zentrum, Munich, Germany

Bastian Zimmer, PhD
Bastian Zimmer

Postdoctoral Fellow - currently: Group leader, Evotec, Hamburg, Germany

So Yeon Koo
So Yeon Koo

Graduate Student

Mohamed Soliman
Mohamed Soliman

Medical Student, Weill Cornell - currently: Physician/Psychiatrist, Ann Arbor, Michigan

Sun Young Chung
Sun Young Chung

Lab Technician - currently: medical student, Harvard University

Chelsea Rittenhouse
Chelsea Rittenhouse

Graduate Student

Elsa Vera
Elsa Vera

Postdoctoral Fellow - currently: Senior Machine Learning Engineer - Digital Intelligence at JPMorgan Chase & Co.

Yuchen Qi
Yuchen Qi

Postdoctoral Fellow - currently: Consultant, The Boston Consulting Group

Sarah Kishinevsky
Sarah Kishinevsky

Graduate Student – currently, Director of the Dean's Entrepreneurship Lab at Weill Cornell

Jiayi Yuan
Jiayi Yuan

Graduate Student

Julius Steinbeck

Postdoctoral Fellow - currently: Freelance Neurologist and Stem Cell Expert, Germany

Yosif Martin Ganat
Yosif Martin Ganat

Postdoctoral Fellow - currently: Research Investigator, Arvinas,, New Haven, CT

Yen Chun "Wenna" Chen
Yen Chun "Wenna" Chen

Research Technician

Sonja Kriks

Postdoctoral Fellow - currently Senior Scientist at Neurona Therapeutics Inc

Jae-won Shim

Postdoctoral fellow - currently: Assistant Prof., Soonchunhayng University

Stuart Chambers

Postdoctoral Fellow - currently, Senior Scientist at Amgen

Justine D. Miller

Principal Scientist at AbbVie, Boston, MA

Fabien Lafaille
Fabien Lafaille

PhD student – currently: Senior Scientist, BlueRock Thearpeutics, New York, NY

Yvonne Gruber Mica

Manager, Field Applications - Cell Biology Thermo Fisher Scientific New York, NY

Inna Lipchina

Graduate Student - currently: Senior Scientist, Cellarity

Gabsang Lee

Postdoctoral Fellow - currently: Associate Prof., Johns Hopkins School of Medicine

Asif Maroof

Graduate Student - currently: Assistant Professor, The University of Texas at San Antonio

Yechiel Elkabetz

Postdoctoral fellow - Currently: Principal Investigator, Max Planck Institute for Molecular Genetics,

Sabrina Desbordes

Postdoctoral fellow - currently: Assistant Prof., Helmholtz Institute

Tiziano Barberi
Tiziano Barberi

Postdoctoral Fellow - Currently: Associate Scientist, Texas BioMed Research Institute, SW National Primate Research Center

Mark J Tomishima, PhD
Mark J Tomishima

Currently, Sr. Director, CNS Bioprocess at BlueRock Therapeutics

Viviane Tabar

Chair, Department of Neurosurgery; Theresa Feng Chair in Neurosurgical Oncology

Anselme Perrier
Anselme Perrier

Postdoctoral Fellow - currently: Principal Investigator, iSTEM, INSERM, France

Hyesoo Kim
Hyesoo Kim

Currently, Assistant Professor at Johns Hopkins School of Medicine

Agnete Kirkeby
Agnete Kirkeby

PhD student – currently, Associate Professor of Stem Cell Biology, University of Copenhagen, Denmark

Lab Affiliations

Achievements

  • ISSCR Achievement Award (2022)
  • Jacob & Louise Gabbay Award in Biotechnology & Medicine (2018)
  • Ogawa-Yamanaka Stem Cell Prize, Gladstone Institutes (2017)
  • MacArthur Fellow (2015)
  • Member, American Society of Clinical Investigation (2014)
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  • Annemarie Opprecht Parkinson Award, Annemarie Opprecht Foundation (2012)
  • Louise and Allston Boyer Young Investigator in Basic Research, Memorial Sloan Kettering Cancer Center (2005)

Lab News & Events

Upcoming event

Genetic, Cellular, and Intercellular Strategies of Human Brain Development

Memorial Sloan Kettering Cancer Center
Rockefeller Research Laboratories
430 East 67th Street
Room RRL-116
New York, NY 10065

Open Positions

To learn more about available postdoctoral opportunities, please visit our Career Center

To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs

Career Opportunities

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Lorenz Studer discloses the following relationships and financial interests:

  • BlueRock Therapeutics
    Intellectual Property Rights; Professional Services and Activities
  • DaCapo Brainscience, Inc.
    Equity; Professional Services and Activities (Uncompensated)
  • Fujifilm Cellular Dynamics, Inc.
    Intellectual Property Rights
  • Luxa Biotechnology, LLC
    Professional Services and Activities
  • Neurona Therapeutics
    Equity; Professional Services and Activities (Uncompensated)
  • Roche
    Professional Services and Activities
  • Rumi Scientific, Inc.
    Equity; Professional Services and Activities (Uncompensated)
  • Vita Therapeutics, Inc.
    Equity; Professional Services and Activities (Uncompensated)

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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