Cell Biology Program
The Philipp Niethammer Lab
The lab focuses on Pre-Regenerative Biology, which comprises the mechanisms by which tissues detect wounds to initiate healing, inflammation, regeneration, and cancer. We address these mechanisms by quantitative imaging in various model systems including live zebrafish.
Katikaneni A, Jelcic M, Gerlach GF, Ma Y, Overholtzer M, Niethammer P. Lipid peroxidation regulates long-range wound detection through 5-lipoxygenase in zebrafish. Nat Cell Biol. 2020 Sep;22(9):1049–1055. PMID: 32868902
Riegman M, Sagie L, Galed C, Levin T, Steinberg N, Dixon SJ, Wiesner U, Bradbury MS, Niethammer P, Zaritsky A, Overholtzer M. Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture. Nat Cell Biol. 2020 Aug 31; PMID: 32868903
Jelcic M, Wang K, Hui KL, Cai X-C, Enyedi B, Luo M, Niethammer P. A Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome. Cell Chem Biol. 2020 Aug 20;27(8):1073–1083.e12. PMID: 32521230
Stoddard M, Huang C, Enyedi B, Niethammer P. Live imaging of leukocyte recruitment in a zebrafish model of chemical liver injury. Sci Rep. 2019 Jan 10;9(1):28. PMCID: PMC6328554
Jelcic M, Enyedi B, Niethammer P. Quantitative imaging of endogenous and exogenous H2O2 gradients in live zebrafish larvae. Methods Mol Biol. 2019;1982:283–299. PMID: 31172479
Philipp Niethammer, PhD
- Cell biologist Philipp Niethammer investigates tissue damage responses with advanced imaging approaches in zebrafish.
- PhD, European Molecular Biology Laboratories & Hamburg University, Germany
- Dorsett L. Spurgeon Distinguished Research Award (2009)
- Louis Gerstner Young Investigator (2012)
- American Asthma Foundation Scholar (2014)
- Louise and Allston Boyer Young Investigator Award (2018)
Lab News & Events
This seminar will be conducted by Zoom Webinar.
Our lab investigates the molecular and physiological mechanisms of how tissues detect wounds to initiate healing, inflammation, regeneration, and cancer (Niethammer et al.
Get in Touch
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
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Philipp Niethammer discloses the following relationships and financial interests:
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