To heal and regenerate, tissues must “know” that they are injured. How wound detection occurs is unclear. If it malfunctions, infection, allergic disease, sterile inflammation, and fibrosis, or cancer may result. What are the first cues that unleash rapid inflammatory and healing responses after injury? We study the elusive Signal 0 of wound detection. We hope that this ultimately will enable us to stop vicious auto-inflammatory circles at the doorstep, or to turn immune cells against tumors.
Philipp Niethammer, PhD
Associate Professor
Research Focus
Cell biologist Philipp Niethammer investigates tissue damage responses with advanced imaging approaches in zebrafish.Education
PhD, European Molecular Biology Laboratories & Hamburg University, Germany- Office Phone: 212-639-5332
- Lab Phone: 212-639-4998
Lab Members
Philipp Niethammer
Principal Investigator
King Lam Hui
Postdoctoral Fellow
Mark J. Jelcic
Graduate Student
Anushka Katikaneni
Research Technician
Zhouyang Shen
Graduate Student
Kalina Belechva
Rotation student
Mildred Perez
Admin Assistant
Publications
- Huang C, Niethammer P. Tissue Damage Signaling Is a Prerequisite for Protective Neutrophil Recruitment to Microbial Infection in Zebrafish. Immunity. 2018 May 15;48(5):1006-1013.e6.
- Jelcic M, Enyedi B, Xavier JB, Niethammer P. Image-Based Measurement of H2O2 Reaction-Diffusion in Wounded Zebrafish Larvae. Biophys J. 2017 May 9;112(9):2011–2018. PMCID: PMC5425381
Selected Achievements
- Dorsett L. Spurgeon Distinguished Research Award (2009)
- Louis Gerstner Young Investigator (2012)
- American Asthma Foundation Scholar (2014)
- Louise and Allston Boyer Young Investigator Award (2018)
