The Stephen Long Lab

Pictured: Stephen Long laboratory

Our laboratory uses a combination of cryo-electron microscopy, x-ray crystallography, and functional approaches to study the mechanisms of eukaryotic ion channels involved in calcium signaling and membrane-embedded enzymes.

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The Stephen Long Lab

Stephen B. Long, PhD

Member

Professor

Research Focus

Stephen Long’s research group studies ion channels and enzymatic membrane proteins.

Education

  • BA, Physics, Amherst College, 1994
  • PhD, Biochemistry, Duke University, 2001
  • Postdoc, Rockefeller University, 2007

Publications

  • Vaisey, G., & Long, S. B. (2018). An allosteric mechanism of inactivation in the calcium-dependent chloride channel BEST1. The Journal of General Physiology, jgp.201812190. (Abstract)
  • Hou, X., Burstein, S. R., & Long, S. B. (2018). Structures reveal opening of the store-operated calcium channel Orai. eLife, 7.  (Manuscript | Atomic Coordinates)
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Selected Achievements

  • Louise and Allston Boyer Young Investigator in Basic Research, Memorial Sloan Kettering Cancer Center (2016)
  • Burroughs Wellcome Career Award in the Biomedical Sciences (2006-2014)