Stephen B. Long: Publications

Stephen B. Long: Publications


View a full listing of Stephen B. Long: Publications’ journal articles.

Delgado B.D. & Long S.B. (2022). Mechanisms of ion selectivity and throughput in the mitochondrial calcium uniporter. Science Advances 

Wang, C.*, Polovitskaya, M.M.*, Delgado, B.D., Jentsch, T. J., & Long, S.B. (2022). Gating choreography and mechanism of the human proton-activated chloride channel ASOR. Science Advances

Jiang, Y., Benz, T. L., & Long, S.B. (2021). Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT. Science

Hou, X.*, Outhwaite, I.R.*, Pedi, L., and Long, S.B. (2020). Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation. Elife 9. (Abstract | Open Conformation Cryo-EM map & Atomic Coordinates). *X. Hou and I.R. Outhwaite are co-first authors.

Wang, C., Jacewicz, A., Delgado, B.D., Baradaran, R., and Long, S.B. (2020). Structures reveal gatekeeping of the mitochondrial Ca(2+) uniporter by MICU1-MICU2. Elife 9. (Abstract | Holocomplex Cryo-EM map & Atomic Coordinates | MICU1-MICU2 complex Cryo-EM map & Atomic Coordinates)

Wang, C.*, Baradaran, R.*, and Long, S.B. (2020). Structure and Reconstitution of an MCU-EMRE Mitochondrial Ca2+ Uniporter Complex. J Mol Biol 432, 5632-5648. (Abstract | MCU-EMRE Cryo-EM map & Atomic Coordinates). *C. Wang and R. Baradaran are co-first authors.

Miller, A. N.*, Vaisey, G.*, & Long, S. B. (2019). Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin. eLife (Abstract | open state Cryo-EM map & Atomic Coordinates).  *A. N. Miller and G. Vaisey are co-first authors.

Vaisey, G., & Long, S. B. (2018). An allosteric mechanism of inactivation in the calcium-dependent chloride channel BEST1. The Journal of General Physiology, jgp.201812190. (Abstract)

Hou, X., Burstein, S. R., & Long, S. B. (2018). Structures reveal opening of the store-operated calcium channel Orai. eLife, 7.  (Manuscript | Atomic Coordinates)

Baradaran, R., Wang, C., Siliciano, A. F., & Long, S. B. (2018). Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters. Nature, 559(7715), 580–584. (Abstract | Atomic Coordinates & Cryo-EM map)

Melinda Diver, Leanne Pedi, Akiko Koide, Shohei Koide, Stephen B. Long (2018). Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT. Nature. Jan 25; 553(7689):526-529. (Abstract | Manuscript | Atomic Coordinates)

George Vaisey, Alexandria Miller, Stephen B. Long. Distinct regions that control ion selectivity and calcium-dependent activation in the bestrophin ion channel. PNAS.  Published online November 7 2016. (Abstract | Atomic Coordinates)

Veronica K. Dickson, Leanne Pedi, Stephen B. Long.  Structure and insights into the function of a Ca2+-activated Cl− channel.  Nature. 2014 Dec 11;516(7530):213-8.  Published online 22 October 2014. (Abstract | Atomic Coordinates)

Melinda M. Diver and Stephen B. Long.  Mutational Analysis of the Integral Membrane Methyltransferase ICMT Reveals Potential Substrate Binding Sites. J Biol Chem. 2014. Sep 19;289(38):26007-20.  Epub 2014 Jul 24 (Abstract)

Xiaowei Hou, Leanne Pedi, Melinda M. Diver, Stephen B. Long. Crystal structure of the calcium release-activated calcium channel Orai. Science. 2012 Dec 7;338(6112):1308-13. Epub 2012 Nov 22. (Abstract | PDF Reprint | Atomic Coordinates)

Alexandria N. Miller and Stephen B. Long.  Crystal structure of the human two-pore domain potassium channel K2P1. Science. 2012 Jan 27;335(6067):416-7. (Abstract | PDF Reprint | Atomic Coordinates)

Long SB, Tao X, Campbell EB, MacKinnon R. Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature. 2007 Nov 15;450(7168):376-82. (Abstract | Atomic Coordinates)

Long SB, Campbell EB, Mackinnon R. Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science. 2005 Aug 5;309(5736):897-903. (Abstract | Atomic Coordinates)

Long SB, Campbell EB, Mackinnon R. Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science. 2005 Aug 5;309(5736):903-8. (Abstract)

Long SB, Casey PJ, Beese LS. Reaction path of protein farnesyltransferase at atomic resolution. Nature. 2002 Oct 10;419(6907):645-50.  (Abstract | Atomic Coordinates: 1KZP  1KZO)