Tammela T, Sanchez-Rivera FJ, Malli-Cetinbas N, Joshi NS, Helenius K, Park YK, Azimi R, Wu K, Kerper NR, Wesselhoeft RA, Gu X, Schmidt L, Cornwall-Brady M, Yilmaz ÖH, Xue W, Katajisto P, Bhutkar A, and Jacks T. A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma. Nature, 545:355-359 (2017).
Roper J*, Tammela T*, Cetinbas N, Akkad A, Almeqdadi M, Wu K, Sánchez-Rivera F, Rickelt S, Park Y, Liang X, Oberli M, Eng G, Roghanian A, Azimi R, Kedrin D., Neupane R., Beyaz S., Sicinska E.T., Bass A., Suarez Y., Yoo J., Chen L., Taylor M.S., Zukerberg L., Katajisto P., Lees J., Deshpande V., Chen J., Hynes R.O., Langer R., Bhutkar A.J., Jacks T., Yilmaz. Ö.H. Epithelial genome editing and orthotopic transplantation models of sequential mutagenesis in colorectal cancer. Nature Biotechnology, 3:569–576 (2017).
Lee JH, Tammela T, Hofree M, Choi J, Marjanovic N, Han S, Canner D, Paschini M, Bhang BH, Jacks T, Regev A, and Kim CF. Anatomically and functionally distinct lung mesenchymal populations marked by Lgr5 and Lgr6. Cell, 70:1149-1163 (2017).
Akama-Garren EH*, Joshi NS*, Tammela T, Chang GP, Wagner BL, Lee D-Y, Rideout WM. III, Papagiannakopoulos T, Xue W, and Jacks T. A modular assembly platform for rapid generation of DNA constructs. Scientific Reports, 18:16836 (2016).
Sánchez-Rivera F*, Papagiannakopoulos T*, Romero R, Tammela T, Bauer MR, Bhutkar AJ, Joshi NS, Subbaraj L, Bronson RT, Xue W, Jacks T. Rapid modeling of cooperating genetic events in cancer through somatic genome editing. Nature, 16:428-31 (2014).
Xue W*, Chen S*, Yin H*, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature, 514:380-4 (2014).
Tammela T*, Zarkada G*, Nurmi H, Jakobsson L, Heinolainen K, Tvorogov D, Zheng W, Franco CA, Murtomäki A, Aranda E, Miura N, Ylä-Herttuala S, Fruttiger M, Mäkinen T, Eichmann A, Pollard JW, Gerhardt H, and Alitalo K. VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signaling. Nature Cell Biology, 13:1202-13 (2011).
Tammela T, Saaristo A*, Holopainen T*, Ylä-Herttuala S, Andersson LC, Virolainen S, Immonen I, and Alitalo K. Photodynamic ablation of lymphatic vessels and intralymphatic cancer cells prevents metastasis. Science Translational Medicine, 3: 69ra11 (2011).
Tammela T and Alitalo K. Lymphangiogenesis: Molecular mechanisms and future promise. Cell 140:460-76 (2010).
Tammela T, Zarkada G, Murtomäki A, Wallgard E, Suchting S, Wirzenius M, Waltari M, Hellström M, Schomber T, Peltonen R, Freitas C, Duarte A, Isoniemi H, Laakkonen P, Christofori G, Ylä-Herttuala S, Eichmann A, Betsholtz C, and Alitalo K. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature, 454:656-660 (2008).
Tammela T, Saaristo A, Holopainen T, Lyytikkä J, Kotronen A, Pitkonen M, Abo-Ramadan U, Ylä-Herttuala S, Petrova T and Alitalo K. Therapeutic differentiation and maturation of collecting lymphatic vessels after lymph node dissection and transplantation. Nature Medicine 13:1458-1466 (2007).