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The Huangfu laboratory uses human pluripotent stem cells (hPSCs) as a powerful genetic model to interrogate the transcriptional and epigenetic mechanisms underlying cell fate decisions in development and disease.
Molecular biologist Simon Powell investigates DNA replication and recombination, chromosome dynamics, and human genetics.
The Vardhana Lab studies how nutrient availability, uptake and metabolism regulates host immune responses during cancer development and immunotherapy.
The Taylor laboratory studies the influence of the nervous system on pediatric and young adult cancers.
Xinbo Yang’s lab applies structural biology and protein engineering to decode T cell receptor specificity in cancer and autoimmune disease.
Led by Dr. Irene Orlow, the Lab participates in self-initiated research and supports investigations from the Population Sciences & Clinical Research programs that involving human specimens processing, testing, and banking. For additional information on current research, publications, and presentations by the Lab, and more, scroll down and click on the ‘View Lab Overview’ or ‘Current Projects’ links.
The Lito lab investigates the properties of oncoproteins that drive cancer cell growth, with a focus on cancers driven by RAS mutations.
Dr. Solomon is an interventional radiologist whose team investigates novel minimally invasive, image-guided therapies and their biologic and immunologic interactions.
The Chiosis lab uses a unique chemical biology approach to understand, diagnose, and treat cellular processes associated with chronic molecular stress, with the ultimate goal of developing novel therapeutic options for use in the clinic.
Immunologist Joseph Sun investigates the natural killer cell response against infection and cancer.