Memorial Hospital Research Laboratories

The Irene Orlow Lab

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Research

Irene Orlow
Irene Orlow, MS, DSc
Attending Biologist

The Molecular Epidemiology Laboratory

Led by Dr. Irene Orlow, the Molecular Epidemiology Laboratory participates in self-initiated research & supports investigations from the Population Sciences Research and Clinical Research programs that involve handling and testing of a variety of human specimens.

Relocation Updates – Summer 2022

As of July 21st 2022, our temporary location is in the Lab Medicine Building @ 327 East 64th ST, 4th floor, NY, NY 10065.  We will return to Main Campus when construction of the new Lab is completed on Schwartz S-10th (~ Febr. 2023). 

*Clinical Research Teams* - we continue accepting biospecimens, as follows: 

- Time sensitive biospecimens requiring immediate processing, weekdays by 4pm*

- Specimens requiring refrigeration but no immediate processing,  weekdays by 4:30pm*

- Saliva specimens (e.g. Oragene kits for DNA/typing), dropped of 24x7 (use designated drop off box)

Reminder: follow the guidelines on email communications for planned biospecimens before, the day off, and to confirm that the sample is on its way to our Lab.

For questions and potential exceptions, get in touch with the Lab.

View Lab Overview

Research Projects

Interested in developing new studies & collaborations with us?

Getting ready for another great day

Getting ready for another great day

Research Assistant, Isidora Autuori, with micropunch

Research Assistant, Isidora Autuori, with micropunch

Processing incoming biospecimens

Processing incoming biospecimens

Running an immunoassay

Running an immunoassay

Inspecting a genotyping chip

Inspecting a genotyping chip

The Orlow Lab

The Orlow Lab

Getting ready for a short celebratory outing

Getting ready for a short celebratory outing

Getting ready for a short celebratory outing

Getting ready for a short celebratory outing

“With a new day comes new strength and new thoughts.” -Eleanor Roosevelt

“With a new day comes new strength and new thoughts.” -Eleanor Roosevelt

Publications

Milic M, Ceppi M, Bruzzone M, Azqueta A, Brunborg G, Godschalk R, Koppen G, Langie S, Moller P, Teixeira JP, Alija A, Anderson D, Andrade V, Andreoli C, Asllani F, Bangkoglu EE, Barancokova M, Basaran N, Boutet-Roninet E, Buschini A, Cavallo D, Costa Pereiera C, Costa C, Costa S, Da Silva J, Del Bo C, Sreckovic V, Djelic N, Dobrzynska M, Durackova Z, Dvorakova M, Gajski G, Galati S, Garcia Lima O, Giovannelli L, Goroshinskaya I, Grindel A, Gutzkow K, Hernandez A, Hernandez C, Holven K, Ibero-Baraibar I, Ottestad I, Kadioglu E, Kazimirova A, Kuznetsova E, Ladeira C, Laffon B, Lamonaca P, Lebailly P, Louro H, Mandina Cardoso T, Macron F, Marcos R, Moretti M, Moretti S, Najafzadeh M, Nemeth Z, Neri M, Novotna B, Orlow I, Paduchova Z, Pastor S, Perdry H, Spremo-Potparevic B, Ramadhani D, Risa P, Rohr P, Rojas E, Rossner P, Safar A, Sardas S, Silva MJ, Sirota N, Smolkova B, Staruchova M, Stetina R, Stopper H, Surikova EI, Ulven S, Ursini CL, Valdiglesias V, Valverde M, Vodicka P, Volkovova K, Wagner KH, Zivkovic L, Dusinska M, Collins AR, Bonassi S.  The hCOMET project: international database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders. Mutat. Res. 2021 Jan-Jun;787:108371. doi: 10.1016/j.mrrev.2021.108371. Epub 2021 Feb 6.

Petruzella S, Bochner BH, Kenney J, Whiting K, Sadeghi K, Benfante N, Cha EK, Dalbagni G, Donahue T, Donat SM, Herr HW, Pietzak E, Orlow I, Ostroff JS, Furberg H. Examining the Accuracy of Self-Reported Smoking-Related Exposure Among Recently Diagnosed Non-muscle Invasive Bladder Cancer Patients. J Urol. 2021 May;205(5):1321-1325. doi: 10.1097/JU.0000000000001571. Epub 2020 Dec 24.

Begg CB, Ostrovnaya I, Geyer FC, Papanastasiou AD, Ng CKY, Sakr R, Bernstein JL, Burke KA, King TA, Piscuoglio S, Mauguen A, Orlow I, Weigelt B, Seshan VE, Morrow M, Reis-Filho JS. Contralateral breast cancers: independent cancers or metastases? Int J Cancer. 2018 Jan 15;142(2):347-356. doi: 10.1002/ijc.31051. Epub 2017 Sep 28. PMCID: PMC5749409.

Orlow I, Shi Y, Kanetsky PA, Thomas NE, Luo L, Corrales Guerrero S, Cust AE, Sacchetto L, Zanetti R, Rosso S, Armstrong BK, Dwyer T, Venn A, Gallagher RP, Gruber SB, Marrett LD, Anton-Culver H, Busam K, Begg CB, Berwick M, GEM study group. The interaction between vitamin D receptor polymorphisms and sun exposure around time of diagnosis influences melanoma survival. Pigment Cell Melanoma Res. 2018 Mar;31(2):287-296. doi: 10.1111/pcmr.12653. Epub 2017 Nov 5. PMCID: PMC5809306.

Pharoah H, Tsai Y-Y, Ramis SJ, Phelan CM, Goode EL, Lawrenson K, …, Orlow I, …, et al. GWAS meta-analysis and replication identifies three novel common susceptibility loci for ovarian cancer. Nat Genet. 2013;45(4):362-70, 370e1-2. PMCID: PMC3693183

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People

Irene Orlow

Irene Orlow, MS, DSc

Attending Biologist

  • Led by Dr. Irene Orlow, the Molecular Epidemiology Laboratory participates in self-initiated research & supports investigations from the Population Sciences Research and Clinical Research programs that involve handling and testing of a variety of human specimens.
  • University of Buenos Aires
[email protected]
Email Address
646-608-8447
Office Phone

Members

Emily Ali
Emily Ali

Research Technician

Jessica Kenney
Jessica Kenney

Research Assistant

Gbemisola Ilelaboye
Gbemisola Ilelaboye

Senior Research Technician

Lab Alumni
Isidora Autuori
Isidora Autuori

Research Assistant

Keimya Sadeghi
Keimya Sadeghi

Research Assistant

Lab Affiliations

Open Positions

To learn more about available postdoctoral opportunities, please visit our Career Center

Career Opportunities

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Irene Orlow discloses the following relationships and financial interests:

No disclosures meeting criteria for time period


The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2021 through disclosure submission in spring 2022). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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