
Human Oncology & Pathogenesis Program
The Santosha Vardhana Lab
Research

The Vardhana lab explores how metabolites regulate immune cell homeostasis, particularly within tumors. We use a combination of traditional immunology, synthetic biology, metabolomics, and bioinformatics to answer fundamental biological questions about the regulation of immune responses with the goal of applying these strategies broadly for the treatment of cancer. Our team is made up of a diverse group of scientists and physicians with backgrounds in immunology, cancer biology, metabolism, and molecular genetics, but we are enthusiastic about integrating members with expertise across physical, life, and computer sciences to achieve our goal of taking novel experimental approaches to understand the complexity of host immunity.
Research Projects

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Publications
People

Santosha Vardhana, MD, PhD
- The Vardhana Lab studies how nutrient availability, uptake and metabolism regulates host immune responses during cancer development and immunotherapy.
- PhD, New York University
- [email protected]
- Email Address
- 646-888-2703
- Office Phone
- View physician profile
- Physician profile
Members






Administrative Assistant

PhD Student

PhD Student

Senior Research Technician

Research Technician

PhD Student

Grad Student

Computational Biologist II

Research Fellow

Research Fellow
Lab Alumni

Research Technician
Lab Affiliations
Achievements
- Chief Medical Oncology Fellow, Internal Medicine, Memorial Sloan Kettering Cancer Center (2014)
- Young Investigator Award, American Society of Clinical Oncology (2016)
- Senior Fellow, Parker Institute of Cancer Immunotherapy (2017)
- Burroughs Wellcome Fund Career Award for Medical Scientists (2019)
- MSKCC Award for Teaching Excellence (2019)
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- NCI K08 Mentored Career Development Award (2020)
- SARS-CoV-2 Research Project Award, Pershing Square Cohn Cancer Research Alliance (2020)
- Josie Robertson Investigator (2021-2026)
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Get in Touch
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Lab Head Email
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Office Phone
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Santosha Vardhana discloses the following relationships and financial interests:
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Immunai Inc.
Professional Services and Activities
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Koch Disruptive Technologies, LLC
Professional Services and Activities
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].