Developmental Biology Program

The Maria Jasin Lab

Research

Pictured: Maria Jasin
Maria Jasin, PhD
William E. Snee Chair

Human chromosomes are constantly assaulted by challenges to their integrity as a result of either environmental agents that damage DNA or from normal DNA metabolism. The failure to repair damaged DNA faithfully is ultimately responsible for many human diseases, especially cancer. This laboratory focuses on the repair of 1 particular lesion in DNA, the double-strand break (DSB). DSBs arise from agents, such as ionizing radiation, and can also occur spontaneously during DNA replication. Our emphasis is on repair of DSBs by homologous recombination, with a particular interest in the role of homologous recombination in maintaining genetic stability. Understanding the repair of DSBs is not only important for basic science and health concerns, but also impacts on molecular genetic manipulations of mammalian genomes.

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Research Projects

Maria Jasin Lab Group

Publications Highlights

People

Pictured: Maria Jasin

Maria Jasin, PhD

William E. Snee Chair

  • The Jasin laboratory focuses on double-strand break repair and genomic integrity in mammalian cells and the relationship to tumor suppression.
  • PhD, Massachusetts Institute of Technology
[email protected]
Email Address
212-639-7438
Office Phone

Members

Maria Jasin, PhD
Maria Jasin

Lab Head

Raymond Wang

Research Assistant

Natalia Bonilla

Sr. Administrative Assistant

Matteo Ferrari
Matteo Ferrari

Senior Research Scientist

Pei Xin  Lim, PhD
Pei Xin Lim

Senior Research Scientist

Darpan Medhi, PhD
Darpan Medhi

Senior Research Scientist

Carmen Perez Calero
Carmen Perez Calero

Research Scholar

Deepika Prasad
Deepika Prasad

Research Associate

Samantha Regan
Samantha Regan

Graduate Student (BCMB)

Travis  White, PhD
Travis White

Senior Research Scientist

Tai-Yuan Yu
Tai-Yuan Yu

Senior Research Scientist

Fang Zhang

Graduate Student (BME)

Lab Alumni
Yufuko Akamatsu

Postdoctoral Fellow

Maria Barbera

Postdoctoral Fellow

Erika Brunet

Postdoctoral Fellow

Francesca Cavallo

Research Fellow

Francesca Cole

Postdoctoral Fellow

Shuhei Ito

Postdoctoral Fellow

Tehone Jackson

Research Technician

Elizabeth Kass, PhD
Elizabeth Kass

Senior Research Scientist

Jan LaRocque

Postdoctoral Fellow

Mary Ellen Moynahan

Associate Member

Conleth Murphy

Postdoctoral Fellow

Koji Nakanishi

Postdoctoral Fellow

Katharina Schlacher

Senior Research Scientist

Deniz Simsek

Graduate Student

Patricia Sung, PhD
Patricia Sung

Senior Research Technician

Fabio Vanoli, PhD
Fabio Vanoli

Research Associate

Yu Zhang

Postdoctoral Fellow

Ercan Akgun

Postdoctoral Fellow

Marco Barchi

Postdoctoral Fellow

Frederic Baudat

Postdoctoral Fellow

Ranjit Bindra

Postdoctoral Fellow

Chun-Chin Chen

Graduate Student

Nicole Christ

Postdoctoral Fellow

Carla M. De Castro Abreu, PhD
Carla M. De Castro Abreu

Research Fellow

Akinori Egashira

Postdoctoral Fellow

Beth Elliot

Postdoctoral Fellow

Weiran Feng
Weiran Feng

Research Fellow

Hildur Helgadottir

Graduate Student

Anita Kapeller

Graduate Research Assistant

Przemek Matt Krawczyk

Visiting Investigator

Alycia Lee

Research Technician

Agnieszka  Lukaszewicz, PhD
Agnieszka Lukaszewicz

Senior Research Scientist

Shaun Peterson, PhD
Shaun Peterson

Research Scholar

Andrew Pierce, PhD
Andrew Pierce

Postdoctoral Fellow

Rohit Prakash, PhD
Rohit Prakash

Senior Research Scientist

Christine Richardson

Postdoctoral Fellow

Peter Romanienko

Graduate Student

Hiroshi Saeki

Postdoctoral Fellow

Jeremy Stark

Postdoctoral Fellow

Lianne Vriend

Graduate Research Assistant

David Weinstock

Postdoctoral Fellow

Ulrica Westermark

Graduate Research Assistant

Lab Affiliations

Achievements

  • National Academy of Sciences (2015)
  • National Academy of Medicine (2016)
  • American Academy of Arts and Sciences (2017)
  • Basser Global Prize for BRCA Research (2018)
  • Shaw Prize in Life Science and Medicine (2019)
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  • Fellow of the AACR Academy (2020)
  • NCI Outstanding Investigator (2020)

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Maria Jasin discloses the following relationships and financial interests:

  • Rutgers New Jersey Medical School
    Professional Services and Activities

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2022 through disclosure submission in spring 2023). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].


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