Ryan Smolkin, PhD

Graduate Student
Ryan Smolkin

Lab Phone

646-888-2344

Dissertation

Plastic Transformation of Developing B Lymphocytes

Start Year

2016

End Year

2025

Education

BS, University of California, Los Angeles

Publications

Chowdhury, P., Belcheva, K. T., Smolkin, R. M., Cols, M., Fontenot, J. D., Yewdell, W. T., & Chaudhuri, J. (2025). IL-2Rα is dispensable for murine B cell development and humoral response. Journal of Immunology, 214(4), 694–702. https://doi.org/10.1093/jimmun/vkae045
 
Sharma, R., Smolkin, R. M., Chowdhury, P., Fernandez, K. C., Kim, Y., Cols, M., Alread, W., Yen, W.-F., Hu, W., Wang, Z.-M., Violante, S., Chaligné, R., Li, M. O., Cross, J. R., & Chaudhuri, J. (2023). Distinct metabolic requirements regulate B cell activation and germinal center responses. Nature Immunology, 24(8), 1358–1369. https://doi.org/10.1038/s41590-023-01540-y
 
Fernandez, K. C., Feeney, L., Smolkin, R. M., Yen, W.-F., Matthews, A. J., Alread, W., Petrini, J. H. J., & Chaudhuri, J. (2022). The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes. eLife, 11, e77073. https://doi.org/10.7554/eLife.77073
 
Yewdell, W. T., Smolkin, R. M., Belcheva, K. T., Mendoza, A., Michaels, A. J., Cols, M., Angeletti, D., Yewdell, J. W., & Chaudhuri, J. (2021). Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection. Cell Reports, 37(6), 109961. https://doi.org/10.1016/j.celrep.2021.109961
 
Yewdell, W. T., Kim, Y., Chowdhury, P., Lau, C. M., Smolkin, R. M., Belcheva, K. T., Fernandez, K. C., Cols, M., Yen, W.-F., Vaidyanathan, B., Angeletti, D., McDermott, A. B., Yewdell, J. W., Sun, J. C., & Chaudhuri, J. (2020). A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization. Immunity, 53(5), 952-970.e11. https://doi.org/10.1016/j.immuni.2020.10.003
 
Nicolas, L., Cols, M., Smolkin, R., Fernandez, K. C., Yewdell, W. T., Yen, W.-F., Zha, S., Vuong, B. Q., & Chaudhuri, J. (2019). Cutting Edge: ATM Influences Germinal Center Integrity. Journal of Immunology (Baltimore, Md.: 1950), 202(11), 3137–3142. https://doi.org/10.4049/jimmunol.1801033

View a full listing of Ryan Smolkin’s journal articles.