Immunology Program

The Jayanta Chaudhuri Lab

Jayanta Chaudhuri, PhD

Laboratory of Molecular and Cellular Immunology

Recombination, genomic integrity, and heterogeneity in B cells

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Featured News

In the Lab

Kalina Belcheva, Teddy Yewdell, Jayanta Chaudhuri, and Ryan Smolkin standing together in a lab

SKI Research Reveals New Insights into Immune Response to Viral Infections — Including COVID-19

Research from Sloan Kettering Institute immunologists suggests that the body may mount an immune response to respiratory viruses that lasts longer than previously thought. The discovery could impact the timing of COVID-19 vaccinations.

At Work: Immunologist Jayanta Chaudhuri

Immunologist Jayanta Chaudhuri has long been interested in biology, Mendelian genetics, and the story of how life evolved.

In the Community

Allysia Matthews, with Citymeals-on-Wheels staff donating reusable ice packs

Giving Supplies a Second Life, and Making an Environmental Impact in the Process

Memorial Sloan Kettering “green” committees focus on waste reduction and energy efficiency throughout the institution while donating useful supplies to New York–area nonprofits.

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Publications Highlights

Sharma, R., Smolkin, R. M., Chowdhury, P., Fernandez, K. C., Kim, Y., Cols, M., Alread, W., Yen, W.-F., Hu, W., Wang, Z.-M., Violante, S., Chaligné, R., Li, M. O., Cross, J. R., & Chaudhuri, J. (2023). Distinct metabolic requirements regulate B cell activation and germinal center responses. Nature Immunology, 24(8), 1358–1369. https://doi.org/10.1038/s41590-023-01540-y

Fernandez, K. C., Feeney, L., Smolkin, R. M., Yen, W.-F., Matthews, A. J., Alread, W., Petrini, J. H. J., & Chaudhuri, J. (2022). The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes. eLife, 11, e77073. https://doi.org/10.7554/eLife.77073

Maekawa, K., Yamada, S., Sharma, R., Chaudhuri, J., & Keeney, S. (2022). Triple-helix potential of the mouse genome. Proceedings of the National Academy of Sciences of the United States of America, 119(19), e2203967119. https://doi.org/10.1073/pnas.2203967119

Yewdell, W. T., Smolkin, R. M., Belcheva, K. T., Mendoza, A., Michaels, A. J., Cols, M., Angeletti, D., Yewdell, J. W., & Chaudhuri, J. (2021). Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection. Cell Reports, 37(6), 109961. https://doi.org/10.1016/j.celrep.2021.109961

Mendoza, A., Yewdell, W. T., Hoyos, B., Schizas, M., Bou-Puerto, R., Michaels, A. J., Brown, C. C., Chaudhuri, J., & Rudensky, A. Y. (2021). Assembly of a spatial circuit of T-bet-expressing T and B lymphocytes is required for antiviral humoral immunity. Science Immunology, 6(60), eabi4710. https://doi.org/10.1126/sciimmunol.abi4710

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People

Jayanta Chaudhuri, PhD

Immunologist Jayanta Chaudhuri studies the mechanisms of immunoglobulin gene diversification.
PhD, Albert Einstein College of Medicine

[email protected]: Email Address
646-888-2357: Office Phone

Members

Jayanta Chaudhuri, PhD — Jayanta Chaudhuri
Principal Investigator

Stephanie Downs-Canner
Assistant Attending Surgeon

Memorial Sloan Kettering Medical Oncologist Jennifer Lue — Jennifer Lue
Assistant Attending

Francesca Manara
Postdoctoral Research Fellow

Laura Nicolas Gomariz, PhD — Laura Nicolas Gomariz
Postdoctoral Research Fellow

Maria Maddalena Perra

Postdoctoral Research Fellow

Ryan Smolkin
Postdoctoral Fellow, Memorial Sloan Kettering Cancer Center

Matthew Kantorski

Research Technician

Lorraine Hernandez Delgado

MSK Bridge Scholar

Veronica Shields
Administrative Assistant

Lab Alumni

Rahul Sharma
Postdoctoral Research Fellow

William Yewdell — William T. Yewdell
Postdoctoral Research Fellow

Zahra Hudda
Pediatric Hematology-Oncology Fellow

Joseph N. Pucella
Faculty Research Instructor, NYU School of Medicine, NYU Langone Medical Center

William Terry

Pediatric Hematology-Oncology Fellow

Kayleigh-Herrick Reynolds
Research Technician

Bao Q. Vuong

Postdoctoral Research Fellow

Urszula Nowak

Graduate Student

Lab Affiliations

Open Positions

To learn more about available postdoctoral opportunities, please visit our Career Center

To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs

Get in Touch

[email protected]

Lab Head Email
646-888-2357

Office Phone
646-422-0495

Office Fax
646-888-2334

Lab Phone
646-888-2614

Lab Phone

Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Jayanta Chaudhuri discloses the following relationships and financial interests:

No disclosures meeting criteria for time period

The information published here is a complement to other publicly reported data and is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.

This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].

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The Jayanta Chaudhuri Lab

Research

Laboratory of Molecular and Cellular Immunology

Featured News

Publications Highlights

People

Members

Open Positions

Postdoctoral Position

Rotation Students

Technician

Get in Touch

Disclosures