The Jayanta Chaudhuri Lab: Publications
Vuong BQ, Herrick-Reynolds K, Vaidyanathan B, Pucella JN, Ucher AJ, Donghia NM, Gu X, Nicolas L, Nowak U, Rahman N, Strout MP, Mills KD, Stavnezer J, Chaudhuri J. A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination. Nat Immunol. 2013; 14: 1183-9.
Matthews AJ, Husain S, Chaudhuri J. Binding of AID to DNA does not correlate with mutator activity. J Immunol. 2014; 193: 252-7.
Pucella JN, Yen WF, Kim MV, van der Veeken J, Luo CT, Socci ND, Naito Y, Iwai, N, Chaudhuri J. miR182 is largely dispensable for adaptive immunity: lack of correlation between expression and function. J Immunol. 2015; 194: 2635-42.
Zheng S, Vuong BQ, Vaidyanathan B, Lin JY, Huang FT, Chaudhuri J. Non-coding RNA Generated following Lariat Debranching Mediates Targeting of AID to DNA. Cell. 2015; 161: 762-73.
Kunimoto H, McKenney AS, Meydan C, Shank K, Nazir A, Rapaport F, Durham B, Garrett-Bakelman FE, Pronier E, Shih AH, Melnick A, Chaudhuri J, Levine RL. Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells. Blood. 2017; 129:1779-1790.
DiMenna LJ, Yen WF, Nicolas L, Sharma R, Saldanha ZN, Chaudhuri J. The transcription factor Sox2 regulates AID expression in class-switched B cells. Cutting Edge: J Immunol 2017; 198: 2244-2248.
Yen WF, Chaudhry A, Vaidyanathan B, Yewdell WT, Pucella JN, Sharma R, Liang Y, Li K, Rudensky AY, Chaudhuri J. BRCT-domain protein BRIT1 influences class switch recombination. Proc Natl Acad Sci USA 2017; 114: 8354-8359.
Vaidyanathan B, Chaudhry A, Yewdell WT, Angeletti D, Yen WF, Wheatley AK, Bradfield CA, McDermott AB, Yewdell JW, Rudensky AR, Chaudhuri, J. The aryl-hydrocarbon receptor controls cell-fate decisions in B cells. J Exp Med 2017 214: 197-20
Matthews AJ, Matthews AJ, Zheng S, DiMenna LJ, Chaudhuri J. Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair. Adv Immunol. 2014; 122:1-57.
Yewdell WT, Chaudhuri J. A transcriptional serenAID: the role of noncoding RNAs in class switch recombination. Int Immunol. 2017; 29:183-196.