Pictured: Kharas Lab

The Kharas lab is working to identify critical pathways in both normal and leukemic hematopoietic stem cells (HSC).

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Pictured: Michael Kharas

Michael G Kharas, PhD

Assistant Professor

Research Focus

Cancer biologist Michael Kharas studies RNA regulators of self-renewal in both normal and leukemic hematopoiesis.

Education

PhD, University of California Irvine

Publications

  • Yousef M, Li N, Nakauka-Ddamba A, Wang S, Davidow K, Schoenberger J, Yu Z, Jensen ST, Kharas MG, Lengner CJ.  Msi RNA-binding proteins control reserve intestinal stem cell quiescence. J. Cell Biol. 2016 October 31: 215 (3): 401–413. PMCID: PMC5100293
  • Wang K, Sanchez-Martin M, Wang X, Knapp KM, Koche R, Vu L, Nahas MK, He J, Hadler M, Stein EM, Tallman MS, Donahue AL, Frampton GM, Lipson D, Roels S, Stephens PJ, Sanford EM, Brennan T, Otto GA, Yelensky R, Miller VA, Kharas MG, Levine RL, Ferrando A, Armstrong SA, Krivtsov AV. Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias. Leukemia. 2016 Jul 1: 31 (1): 151-158  PMCID: PMC5203983
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Selected Achievements

  • American Society of Hematology Junior Faculty Scholar Award (2011)
  • Kimmel Scholar Award (2013)
  • V-Scholar Award (2013)