Center for Cell Engineering

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VIDEO | 07:13
Dr. Michel Sadelain, Director of the Center for Cell Engineering, receives the 2020 Fondation ARC Léopold Griffuel Award for his research on chimeric antigen receptors (CARs) and CAR therapy targeting CD19. Reposted with permission.
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The Center for Cell Engineering (CCE) at Memorial Sloan Kettering Cancer Center was established to foster research on cellular therapies. Our goal is to expand cell engineering research through a collaborative synergy between Memorial Sloan Kettering Cancer Center physicians and scientists.

To attain this goal, the CCE is bringing together researchers who are investigating areas that encompass stem cell engineering, immune cell engineering, cell delivery and bone marrow transplantation, the transfer and regulation of genes in human cells, and gene repair. This physician-scientist partnership draws on researchers from both Memorial Hospital and the Sloan Kettering Institute and will ultimately allow us to devise and implement innovative clinical investigations.

Our mission is to:

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  • Investigate the therapeutic potential of human cell engineering, including the induction, isolation, expansion, differentiation, genetic modification, transplantation, and functional monitoring of therapeutic cells
  • Strengthen the continuum between the biological, translational, manufacturing and clinical dimensions of cell engineering and cell therapy
  • Implement safe and potent immunotherapies and stem cell therapies for an array of hematological malignancies, solid tumors, and non-malignant disorders

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