Molecular Pharmacology Program
The Alex Kentsis Lab
Research

We study the biology of cancers that affect children and young adults ranging from embryonal tumors in infants, leukemias and brain tumors in children, and sarcomas in young adults. Scientists in our group use inter-disciplinary experimental tools as they work to understand the fundamental causes of cancer and to develop definitive therapies for their control. Detailed information about our research is available at http://alexkentsis.net.

Featured News
Publications
Cifani P, Li Z, Luo D, Grivainis M, Intlekofer AM, Fenyö D, Kentsis A. Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics. J Proteome Research, 2021
Takao S, Forbes L, Uni M, Cheng S, Pineda JMB, Tarumoto Y, Cifani P, Minuesa G, Chen C, Kharas MG, Bradley RK, Vakoc CR, Koche RP, Kentsis A. Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia. eLife, 2021
Kentsis A. Why do young people get cancer? Pediatr Blood Cancer, 2020
Ortiz MV, Ahmed S, Burns M, Henssen AG, Hollmann TJ, MacArthur I, Gunasekera S, Gaewsky L, Bradwin G, Ryan J, Letai A, He Y, Naranjo A, Chi YY, LaQuaglia M, Heaton T, Cifani P, Dome JS, Gadd S, Perlman E, Mullen E, Steen H, Kentsis A. Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms’ tumor. JCI Insight, 2019
Ser Z, Cifani P, Kentsis A. Optimized cross-linking mass spectrometry for in situ interaction proteomics. J Proteome Research, 2019
People

Alex Kentsis, MD, PhD
- Cancer biologist and pediatric oncologist Alex Kentsis leads research in the functional proteomics and molecular pharmacology of refractory childhood cancers.
- MD, Mount Sinai School of Medicine
- PhD, New York University
- kentsisresearchgroup@gmail.com
- Email Address
- 1-646-888-2593
- Office Phone
- View physician profile
- Physician profile
Members





Research Technician
Graduate Student
Clinical Fellow

Research Fellow

Graduate Student

Research Fellow

Research Fellow
Research Technician
Graduate Student

Senior Research Scientist

Research Fellow
Senior Research Scientist
Lab Affilations
Achievements
- Louise and Allston Boyer Award for Clinical Research
- Terry Ann Krulwich Physician-Scientist Alumni Award (2020)
- Pershing Square Sohn Prize
- Leukemia & Lymphoma Society Scholar Award (2019)
- Josie Robertson Investigator (2013-2018)
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- St. Baldrick’s Robert J. Arceci Innovation Award
- Elected Member of American Society for Clinical Investigation
- Society for Pediatric Research Young Investigator Award (2018)
- Rita Allen Foundation Scholar Award
- Damon Runyon Cancer Research Foundation Clinical Investigator Award (2016)
- American Society of Hematology Scholar Award (2014)
- Burroughs Wellcome Fund Career Award for Medical Scientists (2013)
- Pediatric Hematology-Oncology Fellowship, Dana-Farber Cancer Institute
- Residency in Pediatrics, Boston Children’s Hospital, Harvard Medical School
- MD, PhD, Mount Sinai School of Medicine and New York University
- AB, SM, University of Chicago
Open Positions
Career Opportunities
Get in Touch
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