![](https://www.mskcc.org/sites/default/files/node/1563/main_image_large/img_1208-1920x384.jpg)
Developmental Biology Program
The Maria Jasin Lab
Research
![Maria Jasin](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/1563/main_image/maria-jasin-photo-1-1-2-1.jpg)
Human chromosomes are constantly assaulted by challenges to their integrity as a result of either environmental agents that damage DNA or from normal DNA metabolism. The failure to repair damaged DNA faithfully is ultimately responsible for many human diseases, especially cancer. This laboratory focuses on the repair of 1 particular lesion in DNA, the double-strand break (DSB). DSBs arise from agents, such as ionizing radiation, and can also occur spontaneously during DNA replication. Our emphasis is on repair of DSBs by homologous recombination, with a particular interest in the role of homologous recombination in maintaining genetic stability. Understanding the repair of DSBs is not only important for basic science and health concerns, but also impacts on molecular genetic manipulations of mammalian genomes.
Research Projects
![Jasin Lab](https://www.mskcc.org/sites/default/files/node/1563/images/circle-line-group-photo-2021.jpg)
Featured News
![X and Y chromosomes in mice](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/197344/main_image/crocodile_3x2.jpg)
![Pictured: Charles L. Sawyers, William Polkinghorn & Simon Powell](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/25999/image/sawyers-polkinghorn-powell.jpeg)
![Pictured: Maria Jasin](https://www.mskcc.org/sites/default/files/styles/width_200/public/node/6639/image/536094.jpg)
Publications Highlights
Georgieva D, Wang N, Taglialatela A, Jerabek S, Reczek CR, Lim PX, Sung J, Du Q, Horiguchi M, Jasin M, Ciccia A, Baer R, Egli D. (2024) BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks. Cell Rep. doi: 10.1016/j.celrep.2024.114006.
People
![Maria Jasin](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/1563/main_image/maria-jasin-photo-1-1-2-1.jpg)
Maria Jasin, PhD
William E. Snee Chair
- The Jasin laboratory focuses on double-strand break repair and genomic integrity in mammalian cells and the relationship to tumor suppression.
- PhD, Massachusetts Institute of Technology
- [email protected]
- Email Address
- 212-639-7438
- Office Phone
Members
![Maria Jasin, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/1988/main_image/maria-jasin-photo-1-1-2-1.jpg)
Lab Head
Research Assistant
Sr. Administrative Assistant
![Matteo Ferrari](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/168757/3x2/ferrari-matteo_08_1200x800.jpg?h=10d202d3)
Senior Research Scientist
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/307166/main_image/alex-jia-headshot.jpg)
Graduate Student WCGS
Graduate Student WCGS
![Darpan Medhi, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/157228/3x2/medhi_180425_06_1200x800.jpg?h=10d202d3)
Senior Research Scientist
![Carmen Perez Calero](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/220696/main_image/perez-calero-carmen_210923_22-1200x800.jpg?h=10d202d3)
Research Associate
![Deepika Prasad](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/192853/main_image/prasad-deepika_210709_05-1200x800.jpg?h=10d202d3)
Research Associate
![Samantha Regan](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/197749/main_image/image001-1200x800.jpg)
Graduate Student (BCMB)
![Travis White, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/127552/3x2/white_180425_10_1200x800.jpg?h=10d202d3)
Senior Research Scientist
Research Fellow
![Tai-Yuan Yu](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/170230/3x2/yu_190117_12_1200x800.jpg?h=10d202d3)
Senior Research Scientist
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/255686/main_image/zhang-fang_500sq.png)
Graduate Student (BME)
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/176602/3x2/pastedgraphic-1.jpg?h=4f77d436)
- University of Rome "Tor Vergata"
![Weiran Feng](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/208408/main_image/feng_180425_12_1200x800_0.jpg)
- Technical University of Graz
- 212-639-8384
- Office Phone
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/25507/3x2/matt-copy.jpg)
- Department of Cell Biology and Histology, AMC Uva, Amsterdam
![Pei Xin Lim, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/127537/3x2/lim_pei_xin_180425_04_1200x800.jpg?h=10d202d3)
- Cornell University
- 212-639-8384
- Office Phone
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/25516/3x2/img_2026-copy-2.jpg)
- Academic Medical Center, Department of Cell Biology and Histology- Amsterdam, The Netherlands
Lab Alumni
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Postdoctoral Fellow
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Postdoctoral Fellow
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Postdoctoral Fellow
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Research Fellow
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/2588/3x2/francesca.jpg)
Postdoctoral Fellow
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/5682/3x2/shuhei.jpg)
Postdoctoral Fellow
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Research Technician
![Elizabeth Kass, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/5680/3x2/kass_180425_07_1200x800.jpg?h=10d202d3)
Senior Research Scientist
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Postdoctoral Fellow
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Associate Member
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Postdoctoral Fellow
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Postdoctoral Fellow
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Senior Research Scientist
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/3620/3x2/deniz.jpg?h=d12bc272)
Graduate Student
![Patricia Sung, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/2933/3x2/sung_180425_09_1200x800.jpg?h=10d202d3)
Senior Research Technician
![Fabio Vanoli, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/5681/3x2/vanoli_180425_07_1200x800.jpg?h=10d202d3)
Research Associate
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/4302/3x2/yu-zhang.jpg?h=10d202d3)
Postdoctoral Fellow
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Postdoctoral Fellow
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Postdoctoral Fellow
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Postdoctoral Fellow
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/134044/3x2/549aea0d-229e-4f42-b1d0-2f627070676d_w0.jpeg?h=10d202d3)
Postdoctoral Fellow
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/25521/3x2/chun-chin_2.jpg)
Graduate Student
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/135391/3x2/nicole-christ-copy.jpg?h=10d202d3)
Postdoctoral Fellow
![Carla M. De Castro Abreu, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/25518/3x2/abreu_180425_08_1200x800.jpg?h=10d202d3)
Research Fellow
Postdoctoral Fellow
Postdoctoral Fellow
![Weiran Feng](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/208408/main_image/feng_180425_12_1200x800_0.jpg)
Research Fellow
Graduate Student
Graduate Research Assistant
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/25507/3x2/matt-copy.jpg)
Visiting Investigator
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/25517/3x2/alycia.jpg)
Research Technician
![Pei Xin Lim, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/127537/3x2/lim_pei_xin_180425_04_1200x800.jpg?h=10d202d3)
Senior Research Scientist
![Agnieszka Lukaszewicz, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/127615/3x2/lukaszewicz_180425_11_1200x800.jpg?h=10d202d3)
Senior Research Scientist
![Shaun Peterson, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/25522/3x2/peterson_180425_06_1200x800.jpg?h=10d202d3)
Research Scholar
![Andrew Pierce, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/135745/main_image/andrew-pierce_1200x800.jpg)
Postdoctoral Fellow
![Rohit Prakash, PhD](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/25508/3x2/prakash_180425_13_1200x800.jpg?h=10d202d3)
Senior Research Scientist
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/135742/3x2/uncclabwithsmile.jpg?h=10d202d3)
Postdoctoral Fellow
![Peter Romanienko](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/135817/main_image/peter-romanienko.png)
Graduate Student
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/134032/3x2/hiroshi-saeki.jpg?h=10d202d3)
Postdoctoral Fellow
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/135397/3x2/stark-jeremy-300x300_0.jpg)
Postdoctoral Fellow
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/25516/3x2/img_2026-copy-2.jpg)
Graduate Research Assistant
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/135739/3x2/david-weinstock.jpg)
Postdoctoral Fellow
![](https://www.mskcc.org/sites/default/files/styles/width_200_1x1/public/node/135316/3x2/ulrica-westermark_profile-photo_crop-2-copy-2.jpg)
Graduate Research Assistant
Lab Affiliations
Achievements
- National Academy of Sciences (2015)
- National Academy of Medicine (2016)
- American Academy of Arts and Sciences (2017)
- Basser Global Prize for BRCA Research (2018)
- Shaw Prize in Life Science and Medicine (2019)
Read more
- Fellow of the AACR Academy (2020)
- NCI Outstanding Investigator (2020)
Open Positions
To learn more about available postdoctoral opportunities, please visit our Career Center
To learn more about compensation and benefits for postdoctoral researchers at MSK, please visit Resources for Postdocs
Get in Touch
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Lab Head Email
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Office Phone
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Lab Phone
Disclosures
Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.
MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.
Maria Jasin discloses the following relationships and financial interests:
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Rutgers New Jersey Medical School
Professional Services and Activities
The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.
This page and data include information for a specific MSK annual disclosure period (January 1, 2023 through disclosure submission in spring 2024). This data reflects interests that may or may not still exist. This data is updated annually.
Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at [email protected].