Developmental Biology Program

The Maria Jasin Lab

Research

Pictured: Maria Jasin
Maria Jasin, PhD

Human chromosomes are constantly assaulted by challenges to their integrity as a result of either environmental agents that damage DNA or from normal DNA metabolism. The failure to repair damaged DNA faithfully is ultimately responsible for many human diseases, especially cancer. This laboratory focuses on the repair of 1 particular lesion in DNA, the double-strand break (DSB). DSBs arise from agents, such as ionizing radiation, and can also occur spontaneously during DNA replication. Our emphasis is on repair of DSBs by homologous recombination, with a particular interest in the role of homologous recombination in maintaining genetic stability. Understanding the repair of DSBs is not only important for basic science and health concerns, but also impacts on molecular genetic manipulations of mammalian genomes.

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Research Projects

Maria Jasin Lab Group

Publications

People

Pictured: Maria Jasin

Maria Jasin, PhD

  • The Jasin laboratory focuses on double-strand break repair and genomic integrity in mammalian cells and the relationship to tumor suppression.
  • PhD, Massachusetts Institute of Technology
212-639-7438
Office Phone

Members

Maria Jasin, PhD
Maria Jasin

Lab Head

Elizabeth Kass, PhD
Elizabeth Kass

Senior Research Scientist

Patricia Sung, PhD
Patricia Sung

Senior Research Technician

Raymond Wang

Senior Research Technician

Natalia Bonilla

Sr. Administrative Assistant

Matteo Ferrari
Matteo Ferrari

Research Fellow

Anita Kapeller

Graduate Research Assistant

Pei Xin  Lim, PhD
Pei Xin Lim

Research Associate

Agnieszka  Lukaszewicz, PhD
Agnieszka Lukaszewicz

Research Associate

Darpan Medhi, PhD
Darpan Medhi

Research Fellow

Rohit Prakash, PhD
Rohit Prakash

Senior Research Scientist

Deepika Prasad

Research Fellow

Samantha Regan

Graduate Student

Travis  White, PhD
Travis White

Research Associate

Tai-Yuan Yu
Tai-Yuan Yu

Research Fellow

Lab Alumni
Yufuko Akamatsu

Postdoctoral Fellow

Maria Barbera

Postdoctoral Fellow

Erika Brunet

Postdoctoral Fellow

Francesca Cavallo

Research Fellow

Francesca Cole

Postdoctoral Fellow

Shuhei Ito

Postdoctoral Fellow

Tehone Jackson

Research Technician

Jan LaRocque

Postdoctoral Fellow

Mary Ellen Moynahan

Associate Member

Conleth Murphy

Postdoctoral Fellow

Koji Nakanishi

Postdoctoral Fellow

Katharina Schlacher

Senior Research Scientist

Deniz Simsek

Graduate Student

Fabio Vanoli, PhD
Fabio Vanoli

Research Associate

Yu Zhang

Postdoctoral Fellow

Ercan Akgun

Postdoctoral Fellow

Marco Barchi

Postdoctoral Fellow

Frederic Baudat

Postdoctoral Fellow

Ranjit Bindra

Postdoctoral Fellow

Chun-Chin Chen

Graduate Student

Nicole Christ

Postdoctoral Fellow

Carla M. De Castro Abreu, PhD
Carla M. De Castro Abreu

Research Fellow

Akinori Egashira

Postdoctoral Fellow

Beth Elliot

Postdoctoral Fellow

Weiran Feng
Weiran Feng

Research Fellow

Hildur Helgadottir

Graduate Student

Przemek Matt Krawczyk

Visiting Investigator

Alycia Lee

Research Technician

Shaun Peterson, PhD
Shaun Peterson

Research Scholar

Andrew Pierce

Postdoctoral Fellow

Christine Richardson Ughetta

Postdoctoral Fellow

Peter Romanienko

Graduate Student

Hiroshi Saeki

Postdoctoral Fellow

Jeremy Stark

Postdoctoral Fellow

Lianne Vriend

Graduate Research Assistant

David Weinstock

Postdoctoral Fellow

Ulrica Westermark

Graduate Research Assistant

Lab Affilations

Achievements

  • National Academy of Sciences (2015)
  • National Academy of Medicine (2016)
  • American Academy of Arts and Sciences (2017)
  • Basser Global Prize for BRCA Research (2018)
  • Shaw Prize in Life Science and Medicine (2019)
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  • Fellow of the AACR Academy (2020)
  • NCI Outstanding Investigator (2020)

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Disclosures

Doctors and faculty members often work with pharmaceutical, device, biotechnology, and life sciences companies, and other organizations outside of MSK, to find safe and effective cancer treatments, to improve patient care, and to educate the health care community.

MSK requires doctors and faculty members to report (“disclose”) the relationships and financial interests they have with external entities. As a commitment to transparency with our community, we make that information available to the public.

Maria Jasin discloses the following relationships and financial interests:

  • Basser Center for BRCA (Penn Medicine)
    Provision of Services

The information published here is for a specific annual disclosure period. There may be differences between information on this and other public sites as a result of different reporting periods and/or the various ways relationships and financial interests are categorized by organizations that publish such data.


This page and data include information for a specific MSK annual disclosure period (January 1, 2019 through disclosure submission in spring 2020). This data reflects interests that may or may not still exist. This data is updated annually.

Learn more about MSK’s COI policies here. For questions regarding MSK’s COI-related policies and procedures, email MSK’s Compliance Office at ecoi@mskcc.org.


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