William T. Yewdell, PhD

Postdoctoral Research Fellow

William T. Yewdell, PhD

Postdoctoral Research Fellow
William  Yewdell

Start Year


End Year



PhD, Stanford University


First Author Publications
Yewdell, W. T., Smolkin, R. M., Belcheva, K. T., Mendoza, A., Michaels, A. J., Cols, M., Angeletti, D., Yewdell, J. W., & Chaudhuri, J. (2021). Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection. Cell Reports, 37(6), 109961. https://doi.org/10.1016/j.celrep.2021.109961
Yewdell, W. T., Kim, Y., Chowdhury, P., Lau, C. M., Smolkin, R. M., Belcheva, K. T., Fernandez, K. C., Cols, M., Yen, W.-F., Vaidyanathan, B., Angeletti, D., McDermott, A. B., Yewdell, J. W., Sun, J. C., & Chaudhuri, J. (2020). A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization. Immunity, 53(5), 952-970.e11. https://doi.org/10.1016/j.immuni.2020.10.003
Yewdell, W. T., & Chaudhuri, J. (2017). A transcriptional serenAID: The role of noncoding RNAs in class switch recombination. International Immunology, 29(4), 183–196. https://doi.org/10.1093/intimm/dxx027
Contributing Author Publications
Mendoza, A., Yewdell, W. T., Hoyos, B., Schizas, M., Bou-Puerto, R., Michaels, A. J., Brown, C. C., Chaudhuri, J., & Rudensky, A. Y. (2021). Assembly of a spatial circuit of T-bet-expressing T and B lymphocytes is required for antiviral humoral immunity. Science Immunology, 6(60), eabi4710. https://doi.org/10.1126/sciimmunol.abi4710
Angeletti, D., Kosik, I., Santos, J. J. S., Yewdell, W. T., Boudreau, C. M., Mallajosyula, V. V. A., Mankowski, M. C., Chambers, M., Prabhakaran, M., Hickman, H. D., McDermott, A. B., Alter, G., Chaudhuri, J., & Yewdell, J. W. (2019). Outflanking immunodominance to target subdominant broadly neutralizing epitopes. Proceedings of the National Academy of Sciences of the United States of America, 116(27), 13474–13479. https://doi.org/10.1073/pnas.1816300116
Nicolas, L., Cols, M., Smolkin, R., Fernandez, K. C., Yewdell, W. T., Yen, W.-F., Zha, S., Vuong, B. Q., & Chaudhuri, J. (2019). Cutting Edge: ATM Influences Germinal Center Integrity. Journal of Immunology (Baltimore, Md.: 1950), 202(11), 3137–3142. https://doi.org/10.4049/jimmunol.1801033
Yen, W.-F., Sharma, R., Cols, M., Lau, C. M., Chaudhry, A., Chowdhury, P., Yewdell, W. T., Vaidyanathan, B., Sun, A., Coffre, M., Pucella, J. N., Chen, C.-C., Jasin, M., Sun, J. C., Rudensky, A. Y., Koralov, S. B., & Chaudhuri, J. (2019). Distinct Requirements of CHD4 during B Cell Development and Antibody Response. Cell Reports, 27(5), 1472-1486.e5. https://doi.org/10.1016/j.celrep.2019.04.011
Yen, W.-F., Chaudhry, A., Vaidyanathan, B., Yewdell, W. T., Pucella, J. N., Sharma, R., Liang, Y., Li, K., Rudensky, A. Y., & Chaudhuri, J. (2017). BRCT-domain protein BRIT1 influences class switch recombination. Proceedings of the National Academy of Sciences of the United States of America, 114(31), 8354–8359. https://doi.org/10.1073/pnas.1708211114
Vaidyanathan, B., Chaudhry, A., Yewdell, W. T., Angeletti, D., Yen, W.-F., Wheatley, A. K., Bradfield, C. A., McDermott, A. B., Yewdell, J. W., Rudensky, A. Y., & Chaudhuri, J. (2017). The aryl hydrocarbon receptor controls cell-fate decisions in B cells. The Journal of Experimental Medicine, 214(1), 197–208. https://doi.org/10.1084/jem.20160789
Casellas, R., Basu, U., Yewdell, W. T., Chaudhuri, J., Robbiani, D. F., & Di Noia, J. M. (2016). Mutations, kataegis and translocations in B cells: Understanding AID promiscuous activity. Nature Reviews. Immunology, 16(3), 164–176. https://doi.org/10.1038/nri.2016.2

View a full listing of William T. Yewdell’s journal articles.