Sirkka Moilanen

Graduate Student

Sirkka Moilanen


Postdoctoral Fellow with Prof. James S. Panek
Department of Chemistry
Boston University

Frank L. Horsfall, Jr. Fellow, 2006–2007

PhD, Cornell University, 2007
Tri-Institutional Training Program in Chemical Biology

BS, Case Western Reserve University, 2001

Thesis: Synthesis of a Structurally and Stereochemically Diverse Spiroketal Library Using Novel Stereoselective Spirocyclizations of C1-Substituted Glycal Epoxides, May 14, 2007


  1. Abstract

    Stereocontrolled synthesis of spiroketals via Ti(Oi-Pr)4-mediated kinetic spirocyclization of glycal epoxides with retention of configuration.
    Moilanen, S. B.; Potuzak, J. S.; Tan, D. S.* J. Am. Chem. Soc. 2006, 128, 1792–1793.
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    (Highlighted in Nature )

  2. Abstract

    Stereocontrolled synthesis of spiroketals via a remarkable methanol-induced kinetic spirocyclization reaction.
    Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* J. Am. Chem. Soc. 2005, 127, 13796–13797.
    [  |   ]

  3. Abstract

    Enantioselective synthesis of erythro-4-deoxyglycals as scaffolds for target- and diversity-oriented synthesis: New insights into glycal reactivity.
    Moilanen, S. B.; Tan, D. S.* Org. Biomol. Chem. 2005, 3, 798–803.
    [  |  ]

  4. TOC

    Discovery and applications of small molecule probes for studying biological processes.
    Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* Biotechnol. Genet. Eng. Rev. 2004, 21, 11–78.
    [  |  |  ]

  5. Abstract

    In vitro stability of α-helical peptide nucleic acids (αPNAs).
    Garner, P.*; Sherry, B.; Moilanen, S.; Huang, Y. Bioorg. Med. Chem. Lett. 2001, 11, 2315–2317.
    [  |  ]

News Articles

27th Annual Convocation Ceremony
MSKCC Center News
Sirkka Moilanen was awarded a Frank L. Horsfall, Jr. Fellowship for 2006-2007. [Full text]

Chemistry: Order of the rings
One of the great challenges in organic chemistry is developing novel ways to synthesize complex structures. The best reactions work for a range of chemical substrates, and give high yields. By these criteria, a reaction, discovered by Derek Tan of the Memorial Sloan Kettering Cancer Center in New York and his co-workers is near ideal. [Full text]