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Sirkka Moilanen Stephan, PhD

Graduate Student

Sirkka Moilanen Stephan

Start Year

2002

End Year

2007

Research Associate, 2012–present
with Prof. Matthias Stephan
Program in Immunology
Fred Hutchinson Cancer Research Center

Postdoctoral Fellow, Boston University, 2007-2009
with Prof. James S. Panek
Department of Chemistry

Frank L. Horsfall, Jr. Fellow, 2006–2007

PhD, Cornell University, 2007
Tri-Institutional Training Program in Chemical Biology

BS, Case Western Reserve University, 2001

Thesis: Synthesis of a Structurally and Stereochemically Diverse Spiroketal Library Using Novel Stereoselective Spirocyclizations of C1-Substituted Glycal Epoxides, May 14, 2007


Publications


  1. Stereocontrolled synthesis of spiroketals via Ti(Oi-Pr)4-mediated kinetic spirocyclization of glycal epoxides with retention of configuration.
    Moilanen, S. B.; Potuzak, J. S.; Tan, D. S.* J. Am. Chem. Soc. 2006, 128, 1792–1793.
    Abstract | PubMed | PMC ]
    (Highlighted in Nature )

  2. Stereocontrolled synthesis of spiroketals via a remarkable methanol-induced kinetic spirocyclization reaction.
    Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* J. Am. Chem. Soc. 2005, 127, 13796–13797.
    Abstract | PubMed  ]

  3. Enantioselective synthesis of erythro-4-deoxyglycals as scaffolds for target- and diversity-oriented synthesis: New insights into glycal reactivity.
    Moilanen, S. B.; Tan, D. S.* Org. Biomol. Chem. 2005, 3, 798–803.
    Abstract | PubMed ]

  4. Discovery and applications of small molecule probes for studying biological processes.
    Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* Biotechnol. Genet. Eng. Rev. 2004, 21, 11–78.
    TOC | PDF | PubMed ]

  5. In vitro stability of α-helical peptide nucleic acids (αPNAs).
    Garner, P.*; Sherry, B.; Moilanen, S.; Huang, Y. Bioorg. Med. Chem. Lett. 2001, 11, 2315–2317.
    Abstract | PubMed ]


News Articles

09/01/2006
27th Annual Convocation Ceremony
MSKCC Center News
Sirkka Moilanen was awarded a Frank L. Horsfall, Jr. Fellowship for 2006-2007. [Full text]

02/02/2006
Chemistry: Order of the rings
Nature
One of the great challenges in organic chemistry is developing novel ways to synthesize complex structures. The best reactions work for a range of chemical substrates, and give high yields. By these criteria, a reaction, discovered by Derek Tan of the Memorial Sloan Kettering Cancer Center in New York and his co-workers is near ideal. [Full text]