Computational & Systems Biology Program
The Dana Pe'er Lab
Research
The Pe’er lab combines single cell technologies, genomic datasets and machine learning algorithms to address fundamental questions in biomedical science. Empowered by recent breakthrough technologies like massive parallel single cell RNA-sequencing, we ask questions such as: How do multi-cellular organisms develop from a single cell, resulting in the vast diversity of progenitor and terminal cell types? How does a cell’s regulatory circuit control the dynamics of signal processing and how do these circuits rewire over the course of development? How does an ensemble of cells function together to execute a multi-cellular response, such as an immune response to pathogen or cancer? We will also address more medically oriented questions such as: How do regulatory circuits go awry in disease? What is the consequence of intra-tumor heterogeneity? Can we characterize the tumor immune eco-system to gain a better understanding of when or why immunotherapy works or does not work? A key goal is to use this characterization of the tumor immune eco-system to personalize immunotherapy.
Featured News
People
Dana Pe'er, PhD
Chair, Computational and Systems Biology Program, SKI; Scientific Director, Alan and Sandra Gerry Metastasis and Tumor Ecosystems Center
- Computational Biologist Dana Pe’er combines single cell technologies, genomic datasets and machine learning techniques to address fundamental questions addressing regulatory cell circuits, cellular development, tumor immune eco-system, genotype to phenotype relations and precision medicine.
- PhD, Hebrew University, Jerusalem Israel
- kornblk@mskcc.org
- Email Address
Members
Instructor, Thoracic Oncology Service
Postdoctoral Researcher
Administrative Assistant II
PhD Student
Assistant Lab Member and Director of SCRI
Research Assistant
Postdoctoral Researcher
Manager, Computational Biologist
Postdoctoral Researcher
PhD Student
Postdoctoral Researcher
Postdoctoral Fellow; Hope Funds for Cancer Research Fellow
Assistant to Chair
PhD Student
Computational Biologist
Senior Research Assistant
Research Assistant
Computational Biologist
Senior Program Manager
Principal Investigator
PhD Student
Postdoctoral Researcher
Postdoctoral Researcher
Senior Computational Biologist
Computational Biologist
Visiting Scientist
Postdoctoral Researcher
PhD Student
Research Assistant
Postdoctoral Researcher
Lab Alumni
Postdoctoral Research Fellow
Postdoctoral Research Fellow
Visiting Scientist
Student
Graduate Student
Graduate Student
Graduate Student
Postdoctoral Researcher
Student
Assistant to the Chair
Research Scholar
Computational Biologist
Postdoctoral Research Fellow
Research Scholar
Postdoctoral Fellow
Research Associate
Scientific Consultant
Senior Bioinformatics Engineer
Research Technician
Postdoctoral Research Fellow
Senior Administrative Assistant
Research Fellow
Senior Research Technician
Administrative Assistant
Postdoctoral Fellow
Lab Affiliations
Achievements
- 2021 Fellow - International Society for Computational Biology (ISCB)
- 2019 Ernst W. Bertner Memorial Award - University of Texas MD Anderson Cancer Center
- 2016 Lenfest Distinguished Faculty Award - Columbia University
- 2014 Director’s Pioneer Award - National Institutes of Health
- 2014 Overton Prize - International Society for Computational Biology (ISCB)
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- 2012 Test of Time Award - Research in Computational Molecular Biology (RECOMB)
- 2010 Innovator Award - Stand Up 2 Cancer/American Academy of Cancer Research (AACR)
- 2009 Packard Fellowship in Science and Engineering - The David and Lucile Packard Foundation
- 2007 NIH Director's New Innovator Award - National Institutes of Health
- 2005 Breakthrough of the Year Runner-up - Science Magazine
- 2005 Career Award at the Scientific Interface - Burroughs Wellcome Fund
