Computational & Systems Biology Program
The Dana Pe'er Lab
Research
The Pe’er lab combines single cell technologies, genomic datasets and machine learning algorithms to address fundamental questions in biomedical science. Empowered by recent breakthrough technologies like massive parallel single cell RNA-sequencing, we ask questions such as: How do multi-cellular organisms develop from a single cell, resulting in the vast diversity of progenitor and terminal cell types? How does a cell’s regulatory circuit control the dynamics of signal processing and how do these circuits rewire over the course of development? How does an ensemble of cells function together to execute a multi-cellular response, such as an immune response to pathogen or cancer? We will also address more medically oriented questions such as: How do regulatory circuits go awry in disease? What is the consequence of intra-tumor heterogeneity? Can we characterize the tumor immune eco-system to gain a better understanding of when or why immunotherapy works or does not work? A key goal is to use this characterization of the tumor immune eco-system to personalize immunotherapy.
Featured News
People
Dana Pe'er, PhD
Chair, Computational and Systems Biology Program, SKI; Scientific Director, Metastasis & Tumor Ecosystems Center
- Computational Biologist Dana Pe’er combines single cell technologies, genomic datasets and machine learning techniques to address fundamental questions addressing regulatory cell circuits, cellular development, tumor immune eco-system, genotype to phenotype relations and precision medicine.
- PhD, Hebrew University, Jerusalem Israel
- Kingl2@mskcc.org
- Email Address
Members
Thoracic Oncology Fellow
Graduate Student
Research Assistant
Graduate Student
Research Fellow
Bioinformatics Engineer
Research Fellow
Postdoctoral Research Fellow
Graduate Student
Assistant to the Chair
Research Scholar
Research Technician
Graduate Student
Senior Research Technician
Associate Lab Member and Director of SCRI
Senior Bioinformatics Engineer
Senior Program Manager
Principal Investigator
Graduate Student
Postdoctoral Researcher
Postdoctoral Research Fellow
Research Fellow
Visiting Scientist
Research Scholar
Graduate Student
Senior Research Technician
Lab Alumni
Postdoctoral Research Fellow
Postdoctoral Research Fellow
Visiting Scientist
Student
Graduate Student
Graduate Student
Student
Postdoctoral Research Fellow
Research Scholar
Postdoctoral Fellow
Research Associate
Research Technician
Postdoctoral Research Fellow
Senior Administrative Assistant
Graduate Student
Senior Research Technician
Administrative Assistant
Postdoctoral Fellow
Lab Affilations
Achievements
- 2014 NIH Director’s Pioneer Award
- 2014 ISCB Overton Prize
- 2012 RECOMB 2012 Test of Time Award
- 2010 SU2C AACR Innovator award
- 2009 Packard Fellowship in Science and Engineering
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- 2007 NIH Directors New Innovator Award
- 2005 Runner up for “Breakthrough of the year”, Science Magazine
- 2005 Career Award at the Interface of Science, Burroughs Welcome Fund