The Derek Tan Lab

Cheng Ji, PhD

Postdoctoral Fellow

Cheng Ji, PhD

Lab Phone


Lab Fax

646-422-0416 (shared)

Senior Scientist, 2015-present
Chicago, Illinois

PhD, University of Notre Dame, 2012

BS, Nanjing University, 2007


  • Designed small-molecule inhibitors of the Anthranilyl-CoA synthetase PqsA block quinolone biosynthesis in Pseudomonas aeruginosa.
    Cheng J.; Sharma, I. ; Pratihar, I.;Hudson, L.; Maura, D.; Guney, T.; Rahme, L. G.; Pesci, E. C.; Coleman, J. P.; Tan, D. S.*; ACS Chem. Biol. 2016
    Abstract | PubMed ]

  • Iron transport-mediated drug delivery: Practical syntheses and in vitro antibacterial studies of tris-catecholate siderophore-aminopenicillin conjugates reveals selectively potent antipseudomonal activity.
    Ji, C.; Miller, P. A.; Miller, M. J.* J. Am. Chem. Soc. 2012, 134, 9898–9901.
    Abstract | PubMed ]

  • Chemical syntheses and in vitro antibacterial activity of two desferrioxamine B-ciprofloxacin conjugates with potential esterase and phosphatase triggered drug release linkers.
    Ji, C.; Miller, M. J.* Bioorg. Med. Chem. 2012, 20, 3828–3836.
    Abstract | PubMed ]

  • Syntheses and biological studies of novel spiropiperazinyl oxazolidinone antibacterial agents using a spirocyclic diene derived acylnitroso Diels−Alder reaction.
    Ji, C.; Lin, W.; Moraski, G. C.; Thanassi, J. A.; Pucci, M. J.; Franzblau, S. G.; Möllmann, U.; Miller, M. J.* Bioorg. Med. Chem. 2012, 20, 3422–3428.
    Abstract | PubMed ]

  • Exploiting bacterial iron acquisition: Siderophore conjugates.
    Ji, C.; Juárez-Hernández R. E.; Miller, M. J.* Future Med. Chem. 2012, 4, 297–313.
    Abstract | PubMed ]

  • Reactivity of the 16e (p-cymene)Ru half-sandwich complex containing a chelating 1,2-dicarba-closo-dodecaborane-1,2-dithiolate ligand towards diynes .
    Xu, Z. W.; Han, L.; Ji, C.; Zhang, R.; Shen, X. J.; Yan, H.* Dalton Trans. 2011, 40, 6992–6997.
    Abstract | PubMed ]

  • Cyclopropanation of nitroso Diels–Alder cycloadducts and application to the synthesis of a 2′,3′-methano carbocyclic nucleoside.
    Ji, C.; Miller, M. J.* Tetrahedron Lett. 2010, 51, 3789–3791.
    Abstract | PubMed | PMC ]

  • A novel dinuclear ruthenium(I)/ruthenium(III) half-sandwich complex containing two chelating 1,2-dicarba-closo-dodecaborane-1,2-dithiolate ligands and its reactivity with alkynes.
    Wu, D. H.; Ji, C.; Li, Y. Z.; Yan, H.* Organometallics 2007, 26, 1560–1562.
    Abstract ]

  • Obacunone.
    Zhou, X.; Ji, C.; Fu, J.; Li, Y. G.* Acta Crystallogr., Sect. E: Struct. Rep. Online 2006, 62, O5544–O5546.
    Abstract ]