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Cancer biologist Nikolaus Schultz uses computational tools to study the diversity of genomic alterations underlying different cancer types.
Physician-scientist Karlo Perica develops cell therapies to treat a wide variety of cancers, focusing on off-the-shelf approaches such as allogeneic CAR T cells and in vivo gene editing.
Jonathan Coleman is a physician-scientist focused on translational research, cancer genomics, and patient-derived organoid models in the study of urologic malignancies. Ongoing work includes the development of local ablative therapies, their influence on the tumor microenvironment, and implications for therapy response.
The Huangfu laboratory uses human pluripotent stem cells (hPSCs) as a powerful genetic model to interrogate the transcriptional and epigenetic mechanisms underlying cell fate decisions in development and disease.
The Vardhana Lab studies how nutrient availability, uptake and metabolism regulates host immune responses during cancer development and immunotherapy.
The Taylor laboratory studies the influence of the nervous system on pediatric and young adult cancers.
Xinbo Yang’s lab applies structural biology and protein engineering to decode T cell receptor specificity in cancer and autoimmune disease.
Led by Dr. Irene Orlow, the Lab participates in self-initiated research and supports investigations from the Population Sciences & Clinical Research programs that involving human specimens processing, testing, and banking. For additional information on current research, publications, and presentations by the Lab, and more, scroll down and click on the ‘View Lab Overview’ or ‘Current Projects’ links.
The Lito lab investigates the properties of oncoproteins that drive cancer cell growth, with a focus on cancers driven by RAS mutations.